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Biomedical subjects

I Romics

Publications and source records attributed to I Romics.

At least 55 records · Page 3Linked to original sources
PubMed1990

[Results obtained by intravesical instillation of BCG in superficial bladder tumors].

The authors carried out immunotherapy in bladder cancer patients in stage pTa-1 G1-2 NoMo. The strain Connaught BCG (120 mg) was instilled weekly for 6 consecutive weeks in 26 patients. Another 13 patients were treated with 150 mg BCG strain Pasteur. The patients were followed average 26 months in the first, 16 months in the second group. The recurring of the tumor were found in 26% and 15% as well. Side effects were experienced more often in the third group. The authors advice the BCG therapy of the superficial bladder cancer.

Administration, Topical↗
PubMed1990

Experience with hormone receptors in renal cancer.

The hormone receptor concentrations in tumour tissues from 20 renal carcinoma patients were determined before postoperative medroxyprogesterone acetate (MPA) therapy was started. Except for glucocorticoid receptors, the concentrations were either not measurable or were extremely low. The question is whether MPA therapy, solely on the strength of its character as a general roborant, is still useful in the treatment of renal tumours, even when it fails to exercise primary influence because of the absence of suitable receptors. None of the 20 patients was treated with MPA.

Antineoplastic Agents↗
PubMed1990

[Zinc, calcium and sodium values in secretions of patients with benign prostatic hyperplasia].

In two randomized patients groups suffering from benign prostatic hyperplasia (BPH) two exprimate samples were drawn at a seven-day interval. In the untreated control group no changes in the values of Ca, Na and Zn were found. In the other group the patients have been treated with ERU capsules (Radicis urticae) for 7 days and thereafter a significant decrease of Zn values were found.

Calcium↗
PubMed1990

A case of funicular schwannoma.

A case of schwannoma in a 55-year-old male patient is reviewed. The diagnostic difficulties are pointed out in view of the literature. Currently, it is still difficult to form a diagnosis without operation either by physical examination or by other diagnostic procedures. That is the authors' point in reviewing their case. The castrated patient has been well and free of complaints for 5 years after operation with no recurrence.

Genital Neoplasms, Male↗
PubMed1989

[Experience with prostate-specific antigen in patients with prostatic cancer].

The authors investigated 71 prostatic cancer patients and 45 BPH patients. The serum concentration of prostatic specific antigen (PSA), the prostatic acid phosphatase (PAP) by radio-immunoassay, the same enzyme (SPP) and the total acid phosphatase (SP) by enzymatic method were determined. In the untreated cancer patients the PSA concentration proved to be pathological in a higher proportion in all stage groups comparing to the results of the PAP, SPP, SP. The clearing of the PSA and PAP concentration on the following days and months after the beginning of the therapy reflects the excellent monitoring capability of the PSA determination. This was demonstrated by several cases too. The authors suggest more frequent use of this method in clinical practice.

Acid Phosphatase↗
PubMed1989

[Malignant schwannoma of the renal capsule].

The authors report on a malignant schwannoma originating in the capsule of the right kidney. By sonography, nephroangiography, cavography, computer tomography and bone scanning, metastases in the kidney or a retroperitoneal tumor could be diagnosed. After transperitoneal exploration, the right kidney and mesenteric metastases were removed. Due to tumor infiltration into the liver and tumor masses in the retroperitoneum, we confined our operation to nephrectomy and palliative excision of retroperitoneal metastases. The patient developed pulmonary metastases postoperatively and died three months after the operation.

Angiography↗
PubMed1989

[Significance of ultrasonic studies in urologic diagnosis].

This report on urological diagnostic is based on more than thousand ultrasonography scans. A set shows the most evident pathological situations in relation to the most evident complaints. The immense possibilities of ultrasound scan in urology are demonstrated through examples and the sense of the scan is discussed. Because there is no harm it is recommended that the ultrasound diagnostic should be used at the beginning of the diagnostic procedures.

Humans↗
PubMed1988

Scintigraphy for the diagnosis of testicular torsion and differential diagnosis of acute intrascrotal processes.

Twenty-five patients suffering from acute painful testicular processes were subjected to scintigraphy. Testicular torsion in the early and delayed phases were diagnosed with 100% accuracy, but one out of 7 cases of epididymitis was wrongly recognized as negative. Interoperative diagnosis in two cases of hydatid torsion proved the foregoing scintigraphic finding to have been wrong. Nevertheless, scintigraphy was found to be reliable in testicular torsion diagnosis.

Acute Disease↗
PubMed1987

Observations with Depo-Provera (medroxyprogesterone) in the management of renal tumours.

A total of 30 patients with renal tumours were started on Depo-Provera (medroxyprogesterone) in December 1981 and followed up for 17 to 44 months. The survivors were checked in July 1985. In 2 of the 13 metastasis-free patients deposits of lethal outcome had formed, survival time averaging 27 months. One of the 8 patients with local metastases had died of renal tumour, average survival time being 26 months. Among the 9 patients with distant metastases there are 2 with survival times of 42 and 44 months, respectively. The liver metastases confirmed by ultrasonography in the first, and in the vena cava in the second case at the time of surgery are no longer demonstrable. Survival time in the last-named group averages 14.5 months.

Adult↗
PubMed1987

Observations with Bazoton in the management of prostatic hyperplasia.

Thirty patients with prostatic hyperplasia stages I and II were administered Bazoton capsules (extract of Radix Urticae) for an average period of 3.5 months. Residual urine, mean and maximal flow were measured before and after treatment. A significant decrease in the volume of residual urine was found. Increase in mean urinary flow was also significant. Maximal urinary flow increased in 50% of the cases. A marked subjective relief was reported by the patients. Bazoton is regarded as suitable for the conservative treatment of prostatic hyperplasia stages I and II.

Humans↗
PubMed1987

Immune studies by the use of Multitest-Merieux in patients with kidney tumours.

Responsiveness to recall antigens was studied by the use of Multitest-Merieux in 20 cases of kidney tumour with and without deposits. The patients of either group, compared with the controls, had depressed scores of immunoreactivity. After surgical removal of the tumour-bearing kidney, immunoreactivity increased, regardless of the presence or absence of deposits. The number of reacting antigens also increased in every case. Lymphocyte transformation in vitro was also depressed, in comparison with the controls before surgery, but after the intervention the transformed blast cells increased in number. Multitest was found suitable for studies of delayed-type sensitivity.

Adult↗
PubMed1987

[Experiences with Depo-Provera (medroxyprogesterone) in the treatment of kidney tumors].

30 patients with renal tumours were treated with Depo-Provera (Medroxyprogesterone). Among the 21 patients operated on without metastases and with an parallel metastasis (fibrous capsule, adipose capsule, peritoneum) in the course of 6 to 15 months no one died of a tumour progression. Among the 9 patients with a distant metastasis in one case the regression of the metastasis could be achieved, whereas in another case progesterone stopped the progression of the intraoperatively observed liver metastasis.

Adult↗
PubMed1986

Study of cytotoxicity against adenovirally transformed cells in patients with tumours of the urinary tract.

Peripheral mononuclear cells of patients with tumours of the prostate and bladder and with papilloma of the bladder were studied for cytotoxicity against adenovirally transformed cell lines. The cytotoxicity of patients with carcinoma of the prostate or bladder revealed no significant changes compared with the control values. Patients with bladder papilloma having received immunostimulant therapy with levamisole over a year showed a significant rise of their cytotoxicity figures in the second 6-month period of study.

Adenoviruses, Human↗
PubMed1985

Effect of levamisol on cellular and humoral immune reactivity and on recurrences in patients with bladder papilloma.

Ten patients who had undergone repeated surgical interventions for bladder papilloma with successive recurrences within intervals of a few months, were given levamisol in weekly doses of 300 mg over a year, and were followed up for various cellular immune reactions, as well as for serum globulin and for acute-phase protein concentrations in the course of treatment. Levamisol was found to act primarily on cell-borne responsiveness. The recurrence-free intervals increased in the course of treatment. Four patients have remained free from recurrences since the start of treatment.

Aged↗
PubMed1984

Study of serum and urine hydroxyproline level of patients with prostatic cancer.

The serum and urine hydroxyproline levels of patients with prostatic cancer were regularly studied for 30 months. Bone metastases were found in 4 patients at the beginning of the study; metastases formed in 8 patients during the test period, and in 9 patients no metastases formed during the study. At the time of X-ray diagnosis of metastasis, significantly higher serum and urine hydroxyproline levels and enzymatic phosphatase were found, but in the tests performed 3 months earlier, in spite of the negative X-ray results, the hydroxyproline results differed significantly from the reference values. The above findings support the use of the hydroxyproline test for the diagnosis of metastases.

Aged↗