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I Robinson

Publications and source records attributed to I Robinson.

60 records · Page 4Linked to original sources
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Cortisol in pregnancy toxaemia of sheep.

Of 31 pregnant ewes with clinical signs of pregnancy toxaemia, 24 had hypoglycaemia and hyperketonaemia at the time that a single blood sample was obtained. Twenty-five of these had a plasma cortisol concentration in excess of 10 ng/ml and six had a value below this. All the seven animals which did not show both hypoglycaemia and hyperketonaemia had a plasma cortisol concentration in excess of 10 ng/ml. Taking all the sheep together, 80% had a high plasma cortisol concentration. This could be the consequence of increased adrenal output or reduced excretion by the liver.

3-Hydroxybutyric Acid↗
PubMedDate not supplied

Identification and partial characterization of common seal (Phoca vitulina) and grey seal (Haliochoerus grypus) interleukin-6-like activities.

Interleukin-6 (IL-6) is a pleiotropic molecule with many important immune modulatory actions. We have investigated the production of biological activity of this cytokine in two species of European seal. IL-6-like activity was detected in supernatants from cultured peripheral blood leucocytes. This IL-6-like activity had an apparent molecular weight of 17-26 kDa, similar to that of human IL-6. IL-6-like activity was also detected in plasma taken from seals with symptoms of systemic infection, but not from apparently healthy seals. Inhibition of this plasma and leucocyte derived activity was accomplished with both rabbit and goat antisera raised against recombinant human IL-6. Further investigation using polymyxin-B showed that this activity was not due to residue LPS present in the supernatants or infected plasmas.

Animals↗
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Pet therapy.

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Animals↗