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Biomedical subjects

I Roa

Publications and source records attributed to I Roa.

At least 91 records · Page 5Linked to original sources

[Nucleolar organizer regions in gastric cancer].

Nucleolar organizer regions may be observed by colloidal silver stains. A considerable increase in the number of regions may be observed in tumors and other pathologic processes as an index of cellular proliferation. Among 20 studies in patients with gastric carcinoma we found a significantly greater number of nucleolar organizer regions in well differentiated tumors as opposed to less differentiated ones. No difference was found in nucleolar organizer regions between seal ring cell tumors and adenocarcinoma.

Adenocarcinoma↗

[The sea blue histiocyte syndrome: a case report].

A young pregnant woman presented with splenomegaly and a hemorrhagic syndrome. A persistent alteration of several coagulation tests was demonstrated. Large foamy pigmented macrophages were shown by bone marrow aspiration. The histopathologic findings are consistent with the sea blue histiocyte syndrome, a benign type of lipid storage disease.

Adult↗

[Gastric cancer in the IX Region of Chile: an analysis of 233 cases].

Gastric cancer is the leading cause of mortality from malignancy in Chile. Different reports indicate a high incidence of well differentiated forms of this tumor. Among 233 endoscopically diagnosed lesions in patients from the Ninth Region of Chile, we found a high incidence of poorly differentiated tumors and a relatively high incidence of signet-ring cell carcinoma. The incidence of inoperable lesions was high.

Adult↗

[Gallbladder pathology in Temuco, IX Region].

We reviewed the histological (light microscopy) findings in 1553 biopsies obtained after surgery for gallbladder disease and correlated these with demographic characteristics of patients. Cancer of the gallbladder was present in 6.1%. Women prevailed in all age and disease groups, especially in mapuches (11:1). Both for neoplastic and nonneoplastic disease the proportion of patients with mapuche surnames was lower than expected for the population in the area. 52% of neoplastic lesions were not macroscopically apparent. Seven tumors involved only the mucous layer and 2 were intraepithelial. Only 2 tumors were well differentiated. The liver was the organ most frequently invaded by gallbladder cancer.

Adolescent↗

[Study and application of the DNA pattern in oncology].

Abnormalities of DNA content are commonly observed in malignant tumors. Clinically relevant information may be obtained given the ease with which DNA pattern can be studied. Flux cytometry and photocytometry are the methods commonly used and both measure the emission of fluorescence after staining the nucleus. ADN pattern has been found to be related to prognosis in many tumors. Also, precancerous lesions and tumor heterogeneity can be analyzed by this technique.

Aneuploidy↗

[Acute plasma cell leukemia].

Plasma Cell Leukemia is a very rare form of plasmocytic dyscrasia, whose clinical and pathological characteristics warrant its recognition as a distinct subentity. We report the case of a 60 years old man who presented a rapidly fatal acute plasma cell leukemia, with multiple osteolytic lesions, hipercalcemia, renal and cardiac failure.

Acute Disease↗

The uncombable hair syndrome.

We report a case of "uncombable hair syndrome" that occurred in a boy who had no other abnormalities. The diagnosis was clinically suspected and confirmed by examination of the scalp hair, which was treated with a bath of gold. Scanning electron microscopy was used for examination. The main defect of the hair was a longitudinal, canalicular depression in one side. The same defect was demonstrated by light microscopy in the transverse cut of the hair embedded in epoxy resin.

Hair↗