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Biomedical subjects

I Ramzy

Publications and source records attributed to I Ramzy.

At least 55 records · Page 3Linked to original sources
PubMed1983

Localized eosinophilic myositis of the masseter muscle associated with actinomycosis.

A case of eosinophilic myositis of the masseter associated with pseudotumor and trismus is presented. Extensive eosinophilic infiltrates of the masseter are rarely observed in the absence of parasitic infection or the hypereosinophilic syndrome. This case is reported because of the rarity of the phenomenon and its importance to the surgeon from the standpoint of differential diagnosis and treatment. The pathogenesis of the condition and its relation to other lesions of muscle associated with eosinophilic infiltration are discussed.

Actinomycosis↗
PubMed1983

Inability of cytoplasmic or nuclear androgen receptor content or distribution to distinguish benign from carcinomatous human prostate.

We used exchange saturation analysis at 15 degrees to quantitate total cytoplasmic and nuclear androgen receptor content of 70 patient specimens. Cytoplasmic androgen receptor contents (fmol/mg DNA) for eight specimens of clinically benign hyperplasia, 14 specimens of histologically hyperplastic prostate obtained at cystoprostatectomy, and carcinomatous and noncarcinomatous prostate obtained at radical prostatectomy for prostatic carcinoma, 48 specimens, respectively, were 830 +/- 165 (mean +/- S.E.), 890 +/- 445, 955 +/- 240, and 750 +/- 95. Nuclear androgen receptor contents of these same specimens, respectively, were 275 +/- 40, 235 +/- 30, 345 +/- 25, and 350 +/- 30; whereas, the values of the cytoplasmic/nuclear receptor content, respectively, were 3.25 +/- 0.55, 3.05 +/- 0.80, 2.50 +/- 0.50, and 2.80 +/- 0.40. Multiway analyses of variance of these cross-sectional data showed that there was no significant difference (p greater than 0.05) between group mean values. This result principally reflects the fact that the families of values for the four tissue groups were highly heterogenous with broad overlap. The results would not appear to be unduly influenced by carcinomatous epithelial cell content of the specimens, because cytoplasmic and nuclear androgen receptor content were not related to specimen carcinomatous epithelial cell content. Paired analyses of receptor content in carcinomatous and noncarcinomatous prostate specimens from the same prostate showed enhanced or unchanged receptor content in 58% (cytoplasmic) and 62% (nuclear) of specimens. Our studies show that cross-sectional analyses of androgen receptor content fail to distinguish carcinomatous prostate from noncarcinomatous prostate. However, paired analyses of these tissues from the same gland identify distinguishing differences. The clinical relevance of these observations remains to be examined.

Cell Nucleus↗
PubMed1981

Ovarian cysts and masses: diagnosis using fine needle aspiration.

The early diagnosis of ovarian tumors is hindered by the inaccessibility of the ovary by noninvasive techniques. The increasing popularity of fine needle biopsy and laparoscopy created a demand for using these techniques to diagnose ovarian masses. Ovarian masses were aspirated prior to, during, or after laparotomy and laparoscopy. The cases included a variety of nonneoplastic cysts and benign and malignant neoplasms. The nuclear and cytoplasmic features of the aspirated cells, the background material and the presence of other structures such as hair, and psammoma bodies and hyaline bodies made it possible to classify most tumors regarding their behaviors as well as their specific type. Malignant neoplasms in general produced more cellular specimens than benign tumors. It was difficult to differentiate between some types of sex cord/stroma neoplasms. Aspiration cytology, which can be performed through a laparoscope transvaginally, transrectally, or transabdominally is a safe, noninvasive, and relatively reliable technique. It should be utilized more in evaluating ovarian masses, when it is desirable to preserve ovarian function in young patients or to minimize surgical trauma to the elderly high-risk patients.

Biopsy, Needle↗
PubMed1980

Epidermoid cyst of the testes.

Malignant tumors of the testis are the leading cause of cancer death in men between 25 and 34 years old. Benign tumors of the testis are rare, accounting for less than 1% of all testicular tumors. We report 2 cases of epidermoid cysts of the testis and review the literature.

Adult↗
PubMed1980

Endometritis following vaginal delivery.

The authors reviewed 158 cases of endometritis complicating vaginal delivery. The diagnostic criteria included fever over 100F with uterine tenderness and/or foul lochia. The mean temperature at diagnosis was 102.2F, and only 21 (13%) had temperature less than 100.9F. The majority of patients did not have traditional risk factors. Endometritis was characterized as generally early in onset (84% within 7 days) and usually mild in course (5.0% had bacteremia, 93.7% responded to initial antibiotics). Yet a small group (1.9%) developed documented pelvic abscess, fulminant peritonitis, or suspected septic pelvic thrombophlebitis.

Adult↗
PubMed1979

Histologic study of ovaries from young women with endometrial adenocarcinoma.

A histologic study of 15 ovaries from patients in whom endometrial adenocarcinoma developed before the age of 40 years was performed. These ovaries were randomized with control groups of 21 age-matched normal ovaries and 25 ovaries from patients who had Stein-Leventhal syndrome. The study was done in an attempt to determine whether the ovaries from these young patients showed any histologic feature that would indicate abnormal ovarian function resulting in unopposed estrogenic stimulation of the endometrium. Histologic features assessed included type and size of cysts, presence and number of primary follicles, corpora lutea, corpora albicantia, and presence of stromal luteinization and sclerosis. Analysis of the results indicated that from a histologic point of view ovaries of patients less than 40 years old who have endometrial adenocarcinoma are more similar to normal ovaries than to polycystic ovaries. Only 11.1% of ovaries of the study group had features suggestive of polycystic ovarian disease.

Adult↗
PubMed1976

Signet-ring stromal tumor of ovary. Histochemical, light, and electron microscopic study.

A peculiar primary ovarian neoplasm occurring in a 28-year-old woman is presented. The tumor cells showed extensive cytoplasmic vacuolation, resulting in a "signet-ring" appearance similar to what was described in Krukenberg tumors. The tumor was studied histochemically, as well as by light and electron microscopy. The cells appeared to be uniform. A moderately electron-dense flocculent material was present in the cytoplasmic vacuoles. similar material was seen in the intercellular matrix with some fibrillary structures suggesting a protein structure. This, coupled with the lack of any basement membrane material around the tumor cells, indicates a mesenchymal tumor that is probably derived from the multipotent ovarian stromal cell. The features that help to differentiate this tumor from other ovarian tumors with clear or vacuolated cells are discussed. Because of its gross and microscopic appearance, the tumor is expected to behave in a benign fashion.

Adenocarcinoma, Mucinous↗
PubMed1976

Sertoli cell tumors of ovary: light microscopic and ultrastructural study with histogenetic considerations.

Two cases of pure Sertoli cell tumors of the ovary are presented. The tumors were grey to brown and generally solid, but with several cystic areas. They showed a highly differentiated, but variable, histologic patterns with solid cords of neoplastic cells, as well as tubular formations. Ultrastructurally, the basal part of the cells rested on a nonfibrillary basement membrane layer while the free border showed occasional cilia. Laterally, the cells showed tight junctions and desmosomes. Abundant rough endoplasmic reticulum and some cystically dilated smooth endoplasmic reticulum were evident. The theories regarding the histogenesis are discussed. Enough similarities, both by light and by electron microscopy, are presented between these tumors and the Sertoli cell to justify classifying these ovarian tumors as Sertoli cell in type. The development of cilia is considered to be a manifestation of focal metaplasia of the neoplastic Sertoli cell.

Cell Nucleus↗
PubMed1976

Verrucous carcinoma of the vagina.

Verrucous carcinoma of the vagina is a highly differentiated and rare variety of squamous-cell carcinoma. Two new cases are presented; a search for the literature revealed three other cases. This neoplasm is characterized by a warty verrucous pattern of growth of squamous epithelium. Histologically, this type of squamous-cell carcinoma is extremely well-differentiated, with minimal evidence of anaplasia of the cells. The neoplasm tends to grow slowly and to infiltrate, sometimes extensively, by pushing rather than by permeating the surrounding tissues. Surgical excision seems to provide the best cure at the present time as the tumor does not respond to irradiation or to podophyllin treatment. Lymph-node dissection is not usually necessary in view of the tendency of the tumor to spread locally rather than to metastasize. However, the value of resection of lymph nodes should be reassessed after enough cases have accumulated.

Carcinoma, Verrucous↗
PubMed1975

Adenoid cystic carcinoma of uterine cervix.

A 68-year-old postmenopausal patient with adenoid cystic carcinoma of the cervic is described. Thirty-two other cases were collected from the literature, and a clinicopathologic analysis for the whole group is presented. The study indicates that a) adenoid cystic carcinoma usually occurs in postmenopausal patients in the commonest presenting problems; c) vaginal cytology was abnormal in most cases in which it was reported; d) the lesion usually forms a mass and infiltrates parametrial and paracervical tissues; e) the tumor is frequently associated with squamous cell carcinoma (in situ or invasive) or other types of cancer; f) local recurrence after radical surgery and /or irradiation, as well as pelvic and widespread metastases, can occur; and g) the histogenesis of this type of tumor is unclear. The various possibilities are discussed.

Aged↗