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Biomedical subjects

I Popescu

Publications and source records attributed to I Popescu.

At least 37 records · Page 2Linked to original sources
PubMed1975

The development of a glucose clamp.

A reliable control system was developed for clamping (i.e., holding at a steady level) the concentration of blood glucose in the hyperglycemic region of a normal nonanesthetized dog. The system is based upon, and hence largely validates, a mathematical model of the canine glucoregulatory mechanism which was assembled from the results of experiments in which radioisotopes were used. The operation of the clamp, however, does not require the use of radioisotopes. The glucose clamp is a tool which may be applicable clinically in the measurement of glucose turnover and in the laboratory in the study of the effects of glucose turnover of variable insulin with constant glucose levels.

Animals↗
PubMed1975

Coronary heart disease and risk factors in some special type collectivities.

Transversal epidemiologic investigations carried out in different populations from several regions of Romania : Gurghiu Valley (lumberjacks from a mountain region), Danube Delta and Razelm lagoon complex (fishermen), and Bucharest have shown that, in spite of the high caloric value of food and even of a high intake of saturated fats, mean serum cholesterol is lower in the rural areas than in Bucharest, probably owing to the strenuous physical work. However, except myocardial infarction, more frequent in the urban than in the rural regions, the other forms of coronary heart disease have a relatively higher frequency in villages, particularly atrial fibrillation and ECG signs of ischemia. These findings might be explained by a greater prevalence of hypertension in these populations. It is concluded that the risk factors, which act synergically, depend on the complex structure of the "ecologic niche".

Adult↗