Macromolecular naloxone: a novel long-acting polymer-bound drug.
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Chemical Phenomena↗
Biomedical subjects
I Parikh
Publications and source records attributed to I Parikh.
Immobilized glucuronosyltransferase for the synthesis of conjugates.
Partially purified rabbit liver UDPglucuronosyltransferase is immobilized on agarose by the cyanogen bromide activation method. Both soluble and matrix-bound enzyme preparations display very similar Km and pH optimum. The storage stability of the immobilized enzyme at 4 degrees is 5-10 times improved over the soluble preparations. The agarose-bound UDPglucuronosyltransferase is successfully used in the synthesis of p-nitrophenyl glucuronide in an overall yield of 50-70%. The matrix-bound enzyme is reusable over an extended period of time and offers an easy and convenient synthetic tool for various drug glucuronides.
Glucuronates↗
An affinity adsorbent for N-acetyl-beta-D-hexosamindiase A.
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Acetamides↗
Noradrenaline binding and the search for catecholamine receptors.
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Adenylyl Cyclases↗
Affinity chromatography--old problems and new approaches.
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Binding Sites↗
A simplified method for cyanogen bromide activation of agarose for affinity chromatography.
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Alanine↗
Topics in the methodology of substitution reactions with agarose.
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Chemical Phenomena↗
Ganglioside-agarose and cholera toxin.
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Aldehydes↗
Affinity chromatography of insulin receptors.
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Adipose Tissue↗
Affinity chromatography of estrogen receptors.
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Animals↗
Substrate analog competitive inhibitors of human renin.
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Amino Acids↗
Affinity chromatography and structural analysis of Vibrio cholerae enterotoxin-ganglioside agarose and the biological effects of ganglioside-containing soluble polymers.
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Adipose Tissue↗
Affinity chromatography and the purification of estrogen receptors.
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Amino Acids↗
Purification of oestradiol receptors by affinity chromatography.
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Animals↗
, -methylene-adenosine 5'-triphosphate. A competitive inhibitor of adenylate cyclase in fat and liver cell membranes.
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Adenine Nucleotides↗
, -Methylene-adenosine-5'-triphosphate--effects of a competitive inhibitor of adenylate cyclase on cyclic AMP accumulation and lipolysis in isolated fat cells.
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Adenosine Triphosphate↗
Enzyme immobilization and adsorbents with biologic specificity.
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Adsorption↗
Adsorbents for affinity chromatography. Use of N-hydroxysuccinimide esters of agarose.
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Acetates↗