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Biomedical subjects

I P Stoicescu

Publications and source records attributed to I P Stoicescu.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[The results of using a simplified questionnaire for determining the prevalence of bronchial asthma].

UNLABELLED: The aim of the study was to assign the asthma prevalence in a Romanian region, by using a simplified questionnaire, easy to fill in by every subject without specialized help. The study included 508 subjects, 280 women (55.1%) and 238 men (44.9%). The subjects proceeded from different industrial areas (cement factory, rubber processing factory, fur and leather manufacture) and from a village (214 subjects). 203 subjects, having symptoms compatible with asthma, performed lung function tests with a Flow Screen Jaeger device, determining VC, FEV1, FEV1% VC, MEF50, MEF25, and pharmacodynamic test if needed (bronchoconstrictor or bronchodilator). RESULTS: about 40% of the subjects mentioned the wheezing, among them 18% wheezing and dyspnea. "Asthmatic bronchitis" is present at 14.8% of the subjects, including 4.5% patients with bronchial asthma diagnosed by a physician (underdiagnosis). The asthma symptoms are more frequent in the factories with exposure to inhaled allergens and air pollution. The most discriminative symptom association for asthma was: wheezing and breathlessness and a history of dyspnea in the last year. These symptoms suggest that the prevalence of asthma could be 10.43%. The positive bronchodilator or bronchoconstrictor function test associated with wheezing, present at 7.48% of the population, seems to better evaluate the prevalence of asthma, which approaches other data already published. The questionnaire we used proved that it can select with acceptable accuracy the individuals to be further investigated with lung function tests.

Adult↗
PubMedDate not supplied

[The bacterial spectrum in bronchopulmonary infections].

UNLABELLED: This study aimed to establish the bacterial profile of bronchopulmonary infections confirmed by the cytobacteriological examination of sputum, in order to find therapeutical guidelines for empirical treatment. We included in the study 408 patients with clinical signs of bronchopulmonary infection (cough and mucopurulent sputum, fever) among which 294 hospitalised patients (5.5% of the 5280 admitted in 1997) and 114 outpatients. The sputum samples collected respecting the decontamination methods were examined cytobacteriologically (smear, culture and antibiogram). The spectrum of isolated bacteria was the following: H. influenzae--198 cases, anaerobes--54, Kl. pneumoniae--53, Ps. aeruginosa--50, S. pneumoniae--17. Analyzing the diseases for which the bacterial examination was performed, we found the following distribution: COPD--66, bacterial infections in TB patients--61, chronic suppurations--33, bronchiectasis--37, pulmonary abscess--24. We noticed the high frequency of H. influenzae and important numbers of anaerobes, Kl. pneumoniae and Ps. aeruginosa especially in COPD patients and patients with chronic suppurations. We performed antibiograms for establishing the sensitivity of bacterial samples (S. aureus, Kl. pneumoniae, Ps. aeruginosa, beta-lactamase-positive H. influenzae). Most of them were multidrug-resistant. CONCLUSIONS: 1. The cytobacteriological study of sputum may be useful for choosing the right treatment, especially for the patients with multiple antibiotic treatments and infected with multidrug resistant bacteria; 2. Knowing the bacterial spectrum in certain respiratory diseases allows the choice of empirical treatment for bronchopulmonary infections in uncomplicated cases.

Anti-Bacterial Agents↗
PubMedDate not supplied

[Recurrent pleural effusion revealing a left atrial myxoma].

A 43 years old woman without any medical history was admitted 8 months before with a right pleural effusion, considered and treated as tuberculous pleurisy, with a good evolution. The recurrence of the right pleural effusion, the reappearance of chest pain, anxiety and nocturnal dyspnea elicited new investigations. The pleural fluid had a low protein content, pleural biopsy was irrelevant. CT scan, bronchoscopy and abdominal ultrasound were of no diagnostic value. Cardiac ultrasound revealed a large left atrial tumor, determining mitral stenosis. The patient underwent surgery, the tumor was excised, the histologic type was myxoma. Three weeks after surgery a right pleural effusion was noticed, this time with high protein content and resolving with non-steroid anti-inflammatory treatment. Pleural effusion never reappeared in the following 6 months. Discussions are made upon the mechanism which determined the pleural effusion in this case.

Adult↗