Our aim was to delineate the effect of various factors, such as sex, age, serum albumin levels, and the timing of gamma-globulin (GG) therapy, on cardiac sequelae of Kawasaki disease. The patients with Kawasaki disease who were reported at the 1995-1996 nationwide survey and received 2000 mg/kg at specified hospitals were selected as the subjects of the study. A total of 2221 patients actually received the basic dose. The relationships of the GG therapy with the cardiac sequelae, sex, age, timing of GG administration (the date of initiation and duration of the regimen following disease onset), and serum albumin levels were examined by using logistic regression analysis. The odds ratios for the cardiac sequelae in patients with Kawasaki disease were high in males (1.63), in those under the age of 1 year (1.54), and in those with a serum albumin level <3.2 g/dl (2.64). The odds ratio was low in those who received GG before day 8 of the illness (0.69) or in those for whom the administration period was for 2 days or less (0.67). To prevent cardiac sequelae of Kawasaki disease it is desirable that GG therapy be started as soon as possible and completed within 2 days.

Age Distribution↗

PubMedDate not supplied

Assessment of the ischemia of the femoral head in idiopathic avascular necrosis. A preliminary report.

Hemodynamic (CATELIX/DF32P system) assessment of circulatory disturbances in idiopathic avascular necrosis (12 femoral heads of 10 patients), demonstrate that vascularity in the necrotic portion was less than 15 per cent (mean, 9%) of normal levels. In 2 cases reassessed after surgery, the recovery of vascularity was to 98 per cent. The vascularity in the translucent portion was fairly well maintained at 50 to 139 per cent. From a histological point of view, vascularity of less than 15 per cent is indicative of ischemia and necrosis of the bone. Hemodynamic methods demonstrate the presence of focal necrosis, long before there are obvious roentgenological abnormalities. The CATELIX/DF32P system is better than the G-M probe/32P system in some respects and is now readily available.

Adult↗

PubMedDate not supplied

X-rays from color television receivers.

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Radiation↗