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Biomedical subjects

I Oesch

Publications and source records attributed to I Oesch.

31 records · Page 2Linked to original sources

[Staged functional closure of bladder extrophy (author's transl)].

Two surgical alternatives exist in the treatment of classic bladder exstrophy: urinary diversion and functional closure. The staged ureterosigmoidostomy is the treatment of choice for patients not suitable for bladder and urethral reconstruction. The treatment of the patients selected for closure begins by closing the bladder during the neonatal period. Osteotomy appears to be necessary in children older than 2 days. Incontinence and vesico-ureteral reflux are treated by bladder neck-urethral reconstruction and reimplantation of the ureters at three years of age. Closure of the epispadias follows in the fifth year. It may be necessary to treat upper tract complications by secondary urinary diversion. Concerning incontinence, technical improvement in artificial sphincter may soon offer an alternative to urinary diversion. The results of 70 primary bladder closures selected from 94 patients presenting with bladder exstrophy are presented: 54 patients with long-term follow-up and completed staged repair were available for assessment: 31 (57.5%) proved to have a good result and 10 (18.5%) to have a fair results. 13 (24.0%) were completely incontinent or required diversion. Failures were thought to be the results of inadequate selection or failure to achieve continence.

Adolescent↗

Esophageal reconstruction with free jejunal grafts: an experimental study.

Replacement of a long segment of esophagus for esophageal atresia or severe stenosis remains a special problem in children. The following studies were designed to test the hypothesis that a section of small bowel without serosa could survive as a free autologous transplant to replace part of the mediastinal esophagus. Laparotomy was performed in 20 adult cats, a loop of small bowel was resected and an end-to-end jejunojejunostomy was completed. The serosa of the resected bowel was removed and the mucosa-muscularis graft was used to replace a segment of the middle esophagus that was resected via a right thoracotomy. The interposed graft was entirely wrapped with adjacent skeletal muscle flaps. Postoperative studies include barium swallow and cine esophagograms, histology and blood vessel casts. Results are presented which show anatomical and functional survival of 16 grafts without blood vessel anastomoses or intrinsic vascular pedicles.

Animals↗

[Spontaneous colon perforation in patients with chronic kidney failure].

Although spontaneous colonic perforation is a rare event, if has recently been observed with increasing frequency in patients with renal failure. Several of the drugs given to such patients may induce dehydration of faeces; the combination of very hard faecal masses and an abnormal fragility of the uraemic intestinal mucosa will then lead to the formation of a decubital ulcer. Prophylaxis or at least early diagnosis are imperative because after completed perforation the prognosis is very poor. The operative method of choice is the incontinuous resection of the entire segment of the colon affected by faecal impaction.

Adult↗

[Methods of local excision of rectal neoplasms].

Recent experience in the behaviour of rectal carcinomas allows local tumour excision under certain conditions to be carried out as a "total excision-biopsy in healthy tissue". The indication for operation depends on criteria referring to the tumour as well as to the patient. The operation technique is that of transanal excision. Brief survey of personal results.

Humans↗

[Complications following colon surgery].

615 transperitoneal operations on the colon and rectum produced the following results. 377 abdominoperineal resections, anterior resections, partial and subtotal colectomies and proctocolectomies, 87 closures of colostomies and 151 operations with resection. 66% of the operations were required due to tumors. The death rate with 545 preopreratively prepared and scheduled operations was 8.1% whereas with the 70 emergency operations it was 25.7%. In 254 or 41.3% of the cases there were postoperative complications. Severe postoperative complications due to infection were the most frequent, followed by cardiopulmonary, haemorrhagic, urological and complications due to ileus. The quotient of insufficiency with the 356 anastomoses was 16%, the death rate 1.4%.

Abscess↗