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Biomedical subjects

I Nagy

Publications and source records attributed to I Nagy.

316 records · Page 18Linked to original sources

Nuclear magnetic resonance study of changes induced by the energy of ultrasonic field in the lungs.

156 laboratory mice were exposed to ultrasonic (US) waves under 12 different conditions. After exposure to ultrasounds, the left lung of each animal was studied morphopathologically and then analysed by nuclear magnetic resonance (NMR) spectroscopy. The study emphasized the possibility of hemorrhagical lesions in the lung through US and the fact that both measurement techniques (for T1 and T2) are alike in sensitivity. The effect on the lung is depending on the intensity and time of exposure to US.

Animals↗

Vasoactive hormones in familial pheochromocytoma with predominant norepinephrine secretion.

A family was investigated with an increased occurrence of pheochromocytoma. Three males out of 7 family members showed biochemical and morphological evidence of catecholamine-secreting tumor. Plasma concentrations of norepinephrine, aldosterone, arginine vasopressin and renin activity, as well as urinary excretion of norepinephrine, were enhanced in all the 3 patients. The plasma level of atrial natriuretic peptide decreased. After surgical removal of the tumor the hormonal alterations tended to be normalized; however, plasma concentration of norepinephrine remained above normal. The elevated plasma norepinephrine was postoperatively accompanied by slightly increased urinary norepinephrine excretion in 1 patient without any detectable tumor. The severity of the disease was most pronounced in the youngest patient, while in the oldest one a 'silent' pheochromocytoma was found. The occurrence of familial pheochromocytoma in successive generations may suggest an autosomal-dominant inheritance.

Adolescent↗