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Biomedical subjects

I Morrison

Publications and source records attributed to I Morrison.

104 records · Page 6Linked to original sources
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Ovine ceroid-lipofuscinosis: a model of Batten's disease.

An inherited neurological disease of sheep was characterized by the intracellular accumulation of autofluorescent lipopigments in neurones and a wide variety of other cells within the body. The staining, fluorescent, ultrastructural and physical characteristics of the storage material were similar to those found in a heterogeneous group of storage diseases of children known as Batten's disease or the ceroid-lipofuscinoses. The ovine disease did not exactly fit any of the main human entities, but had features in common with both the late infantile and juvenile forms. It was concluded that this was a useful model for studying the pathogenesis of this type of storage disease and for therapeutic trials. A flock of sheep is maintained for this purpose.

Animals↗
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Hamster health care.

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Budgets↗
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Complete resolution of CMV-associated acute hydramnios by single large volume reduction amniocentesis and maternal indomethacin. A case report.

Acute hydramnios is a rare complication of pregnancy, usually of idiopathic etiology and associated with a very poor perinatal prognosis. In this single case report, acute hydramnios at 21 weeks' gestation, associated with fetal CMV infection, was treated by a single large volume reduction amniocentesis combined with maternal indomethacin therapy and result in delivery of a near term survivor.

Adult↗
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The cost of laboratory technology: a framework for cost management.

Laboratory costs at Vancouver General Hospital have been increasing over the past decade. Of the numerous explanations that have been offered for these increases, one contributing factor is the impact of automation and technology. An aggregate measure of laboratory technology was constructed and the net contribution to cost per acute care admission was estimated. Technology has two counteracting effects: It stimulates demand for tests, thus increasing cost per acute care admission, and it increases productivity, thus reducing costs. Effective management may be able to achieve the cost reductions without incurring an increased demand.

Automation↗