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Biomedical subjects

I Mínguez

Publications and source records attributed to I Mínguez.

12 recordsLinked to original sources

[Study and incidence of carcinoma of the larynx in women].

Recent publications show an increase in the frequency of laryngeal carcinoma in women. Previous studies of patients in our health district (1875-1994) showed a male/female ratio of 56/1. However, a retrospective study of all laryngeal carcinomas diagnosed in a recent year (June 1997-May 1998) showed an overall male/female ratio of 10/1. Women are older at time of diagnosis than men (mean 70.33 years). None of the women was a regular drinker and only one smoked. Glottic location and absence of metastatic lymph node enlargement predominated at time of diagnosis.

Adult↗

Double labeling immunohistological study of African swine fever virus-infected spleen and lymph nodes.

To identify cells in situ in which African swine fever (ASF) virus is present, a double immunohistological labeling technique was used on sections of ASF-infected spleen and lymph nodes. Cells were identified by an indirect immunoalkaline phosphatase technique using monoclonal antibodies (MoAb) reactive against different leukocyte subsets. ASF virus, detected by a direct immunoperoxidase method using swine immunoglobulin G (IgG) anti-ASF virus antigens, was not present in T helper or in T cytotoxic/suppressor lymphocytes, whereas it was detected in tissue macrophages that reacted with different MoAb (74-22-15, C4, A7, and F2). A large number of cells strongly reactive with MoAb 74-12-4 (T helper lymphocytes) were found in the marginal zone in infected spleen. In infected lymph nodes, these intensely stained cells were found in small numbers. Cells reactive with MoAb 76-2-11 (T cytotoxic/suppressor lymphocytes) were less stained in infected spleen and lymph nodes than in non-infected organs.

African Swine Fever↗

Eosinophilic granuloma of the jaws: a report of three cases.

Three cases of eosinophilic granuloma involving two boys and a girl are reported. Osteolytic lesions of the jaws were seen in all three patients. The two boys presented mandibular lesions, while the girl had lesions in both jaws. Patient age at the onset of the disease was 6 and 9 years in the boys and 10 years in the case of the girl. The affected zone was painful to palpation in all cases, with intra- and extraoral swelling and bone bulging that caused slight facial deformity and bleeding of the gums. Biopsies were obtained in all three cases, and the histopathological study confirmed the diagnosis. The clinical course was favorable in all three children.

Age Factors↗