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Biomedical subjects

I M Raber

Publications and source records attributed to I M Raber.

24 records · Page 2Linked to original sources
PubMed1987

Acute band keratopathy following intracameral Viscoat.

Band keratopathy developed rapidly in two patients following uneventful phacoemulsification and intraocular lens implantation using BSS Plus (balanced salt solution enriched with glutathione, bicarbonate, and glucose) infusion and Viscoat (chondroitin sulfate-sodium hyaluronate), which was left in the anterior chamber at the conclusion of the procedure. Histopathologic evaluation of corneal tissue obtained from one patient at the time of edetic acid chelation revealed histochemical findings consistent with anterior stromal calcification. To investigate a possible relationship between Viscoat and the rapid onset of band keratopathy, Viscoat formulated with varying concentrations of phosphate buffer was injected intracamerally into 42 rabbit eyes. Within 48 hours, clinically obvious corneal opacification developed in nine (47%) of 19 eyes injected with the commercial preparation of Viscoat. Also, similar opacification developed in ten (77%) of 13 eyes that received Viscoat formulated with twice the phosphate concentration of the commercial preparation. Band keratopathy did not develop any of ten eyes that received Viscoat with one fourth the commercial phosphate concentration. In selected opacified corneas, the presence of phosphorus in the subepithelial and posterior corneal stroma was confirmed by histochemical stains and energy-dispersive x-ray analysis.

Aged↗
PubMed1984

Scleritis, pericarditis, and aortic insufficiency in a patient with rheumatoid arthritis.

A 55-year-old black man developed anterior nodular scleritis in his left eye in November 1981. He had no symptoms of systemic disease, and initial laboratory tests revealed only a positive rheumatoid factor. Fourteen months later he presented with pericarditis and aortic insufficiency requiring aortic valve replacement. Examination of excised valvular and pericardial tissue showed changes compatible with rheumatoid disease. Shortly after the surgery he developed florid rheumatoid arthritis. The clinical course of this patient illustrates how scleritis can be the initial sign of severe systemic disease.

Aortic Valve↗
PubMed1980

Traumatic wound dehiscence after penetrating keratoplasty.

Twelve cases of traumatic wound dehiscence occurred in ten patients after penetrating keratoplasty. Nine of the ten patients were males between the ages of 11 and 44 years. Ten of the 12 traumatic wound ruptures occurred with the sutures in place. Final visual acuity was better than 6/60 in only four patients. The grafts have remained clear in six of the ten patients, while one patient awaits a regraft. Four patients required repeat keratoplasty. The primary cause of visual failure was damage to the retina and posterior segment. the importance of protecting the eye after corneal transplantation is stressed.

Adolescent↗