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Biomedical subjects

I M Bali

Publications and source records attributed to I M Bali.

32 records · Page 2Linked to original sources

Effect of coagulating and cutting current on a demand pacemaker during transurethral resection of the prostate. A case report.

Electromagnetic interference from diathermy apparatus can be a real hazard in a patient with a demand pacemaker. A case is reported in which the cutting current of transurethral electrocautery deactivated an implanted pacemaker, while coagulating current did not alter pacemaker activity. Therefore frequent short bursts of cutting current were used for successful resection of the prostate. This case emphasizes the need for vigilant care of patients with demand pacemakers requiring transurethral resection.

Electrocardiography↗

Immediate changes in plasma potassium, sodium and chloride concentrations induced by suxamethonium.

Four groups of healthy female patients were anaesthetized with wither thiopentone, Althesin or nitrous oxide-oxygen with and without halothane. The concentrations of the plasma electrolytes were measured before and at varying times up to 10 min after the administration of suxamethonium 1 mg/kg. Asmall, but significant, biphasic increase in plasma potassium concentration was found when suxamethonium was administered to patients in whom anaesthesia was induced with thiopentone, Althesin and nitrous oxide-oxygen. The initial increase in plasma potassium concentration was greater in the Althesin group thanin the other two groups. A more delayed, but sustained, increase in plasma potassium concentration was found following induction with nitrous oxide-oxygen-halothane. There were no significant changes in the plasma concentrations of sodium or chloride exceptin the halothane-nitrous oxide-oxygen series.

Adult↗

The effect of modified electroconvulsive therapy on plasama potassium concentration.

The influence of modified Type 11 electroconvulsive therapy (ECT) on plasma potasium was studied in 60 patients anaesthetized with a barbiturate and suxamethonium and the finding compared with a "control" group of patients having the same anaesthesia but not ECT. In the ECT series, plasma potassium concentration increased to a maximun 1 min after suxamethonium fasciculations and this increase occurred earlier and was more marked than that observed in the control group. It was also slightly shorter in duration, as was the comparable period of respiratory depression. These findings can be accounted for by the synchronous contraction of muscles containing blood with an increased potassium concentration following suxamethonium.

Adult↗

Studies of drugs given before anaesthesia XXV: Medazepam, a new benzodiazepine.

Medazepam, a new benzodiazepine, was studied as an oral preanaesthetic medication in adult women in a dose of 10 mg, and the findings compared with those obtained with diazepam 10 mg or a dummy capsule using a double-blind technique. In the doses used medazepam produced less drowsiness than diazepam and was no more anxiolytic than the placebo.

Administration, Oral↗

The effect of non-depolarizing relaxants on plasma potassium.

Plasma potassium concentrations were measured in four groups of unpremedicated patients in whom anesthesia was induced with thiopentone 5 mg/kg followed by tubocurarine 0.5 mg/kg, gallamine 2 mg/kg, pancuronium 0.1 mg/kg or AH 8165 1.25 mg/kg, prior to elective dental surgery. There was a small but consistent decrease in plasma potassium following the injection of pancuronium and, to a lesser extent, following gallamine. No changes were found during the first 10 min following tubocurrarine. With AH 8165 there was an early reduction in plasma potassium but the values returned to within normal limits by 5 min.

Adult↗

The source of increased plasma potassium following succinylcholine.

Increases in plasma potassium following succinylcholine have been reported by many workers. In the present studies, these are greater when Althesin is used as the induction agent than after thiopental, and the rise is particularly marked in patients given halothane, occurring earlier in patients having electroshock therapy, and being reduced by the prior administration of a small dose of tubocurarine. These findings suggest that the rise in potassium is due to muscle trauma indiced by the relaxant during the period of fasciculation, and this is confirmed by an increase in creatine phosphokinase enzyme activity. Althesin and halothane are best avoided with succinylcholine in chronic catabolic states where an excessive rise in plasma potassium could lead to dangerous cardiac dysrhythmias.

Creatine Kinase↗

Corneal abrasions during general anesthesia.

The eyes of 200 healthy adult patients undergoing general anesthesia were stained with fluorescein strips for detection of corneal abrasion in the immediate postoperative period. Twenty-six of 59 patients in whom the eyes remained partly open showed positive staining--an incidence of 44 percent. The remaining 141 patients in whom the eyes were naturally closed or protected with adhesive tape or vaseline gauze did not develop exposure keratitis. It is suggested that covering of eyes is necessary in all cases undergoing general anesthesia so as to avoid this frequent complication of anesthesia.

Adult↗