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Biomedical subjects

I Lincir

Publications and source records attributed to I Lincir.

11 recordsLinked to original sources

Anticaries effect of different amine fluoride concentrations in schoolchildren.

A double-blind 3-year clinical trial was conducted in a nonfluoridated water community in which 354 schoolchildren aged 9-10 years were assigned randomly to three groups (A, B and C) and subjected to a treatment with 1 of 3 different concentrations of amine fluoride solution every 2 months. Clinical examinations were conducted at baseline and after 1, 2, and 3 years. For group A (positive control) receiving topical applications of amine fluoride solution (1%), the 3-year DMFT and DMFS increments were 4.0 +/- (SD) 2.7 and 8.5 +/- 5.6, respectively. For group B (0.5% F), the DMFT and DMFS increments were 4.4 +/- 3.0 and 8.4 +/- 5.7, respectively; these differences being statistically not significant. The mean caries increments in group C (0.25% F) were 5.1 +/- 2.9 for DMFT and 10.0 +/- 5.5 for DMFS. The differences in incremental caries scores between group C and groups A or B were statistically significant (p < 0.05). Thus, the amine fluoride solution, in which the fluoride content was reduced by half, provided similar caries reductions in schoolchildren as did a standard amine fluoride solution with 1.0% F.

Amines

Caries-preventive effect of two different topical fluoride concentrations with two different frequencies of application in preschool children.

The effects of standard topical amine fluoride solution (1% F) and a low-fluoride solution (0.5% F) with two different frequencies of application (5 and 10 times a year) on 2 years dental caries increment were compared in a double-blind clinical trial involving 199 kindergarten children. The results suggest that increased frequency of application of a low fluoride topical solution (10 times a year) may provide caries protection in preschool children with relatively high caries activity.

Analysis of Variance

[Dentist's patient under antineoplastic therapy].

The side effects of antineoplastic drugs can be manifest in the oral cavity. Every dentist must be familiar with these groups of drugs and their mechanisms of action and the management of their adverse oral manifestations. The most common oral reactions to administered antineoplastic drugs are: mucositis, local or generalized infections and hemorrhages. The right way in which these manifestations may be handled therapeutically can ensure dentist's patient a langer life of better quality.

Antineoplastic Agents

[Topical fluorides--possible side effects].

The use of topical fluoride products is established as an effective method in caries prevention and might be a considerable extra source of fluoride. Following the use of topical fluoride products variable amounts of fluoride are swallowed and adsorbed into the systemic circulation, amounts which may be sufficient to produce some effects on physiologic and biochemical processes like dental fluorosis, changes in the structure and function of the gastric mucosa, kidney function and plasma and tissue cAMP levels. These possible side effects are all, except that of dental fluorosis, transient and reversible. For the purpose of enhancing the safety of topical fluoride application, several recommendations are mentioned all of which are designed to reduce the ingestion and absorption of fluoride.

Fluorides, Topical