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Biomedical subjects

I Levy

Publications and source records attributed to I Levy.

128 records · Page 8Linked to original sources

The impending Canadian prostate cancer epidemic.

PURPOSE: To model and forecast prostate cancer incidence and mortality in Canada to the year 2016. METHODS: Bivariate multiplicative models of prostate cancer incidence and mortality for Canadian men aged 45 years or older, linear in time and Weibull in age, were fitted using weighted non-linear regression. RESULTS: The number of incident cases of prostate cancer is forecast to increase from 11,355, observed in 1990, to 26,900 by the year 2010 and to 35,200 by the year 2016. The number of deaths are estimated to climb from 3,424, observed in 1991, to an estimated 6,300 by the year 2010, and to 7,800 by the year 2016. CONCLUSIONS: The dramatic increase in prostate cancer rates with age, coupled with the expected large increase in the elderly Canadian male population and steadily increasing prostate cancer incidence rates will produce very large increases in the number of men who will have prostate cancer over the next 20 years. This has important implications for health care delivery in the future.

Age Distribution↗

Legionella pneumonia in neonates: a literature review.

It has recently been recognized that neonates may develop pneumonia as a result of Legionella pneumophila. The objective of this study is to characterize the epidemiology, risk factors, diagnosis, clinical features, and outcome of neonatal legionellosis. Review of the literature revealed nine cases of neonatal Legionella infection. Five neonates were term infants and four were preterm. Eight had potential risk factors such as prematurity, congenital heart disease, bronchopulmonary dysplasia, or corticosteroid therapy. Diagnosis was proven by culture in all cases. The main presentation was acute respiratory distress requiring mechanical ventilation. In six infants, the infection had a fatal outcome, including five who were not treated with erythromycin. All the cases were nosocomial, and environmental Legionella was documented in five cases. As has been noted in adults and children with Legionella, early recognition and institution of appropriate therapy are the most important determinants of the prognosis.

Adult↗