Biomedical subjects
Publications and source records attributed to I Leusen.
Experiments in rats during acute and prolonged periods of hypercapnia show important changes in the glutamate and glutamine content of the brain. Compartmentation studies using labelled glutamate intracisternally injected show an increased turnover of the small glutamate compartment. The possible pathophysiological significance of these observations is discussed.
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Incubated rat testes produce not only testosterone but also 7 alpha-hydroxylated and 5 alpha-reduced testosterone metabolites. The ratio of the metabolites is modified progressively during the maturation of the testes and is also profoundly altered by the administration of HCG in adult rats.