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Biomedical subjects

I Jung

Publications and source records attributed to I Jung.

31 records · Page 2Linked to original sources
PubMedDate not supplied

Molecular mechanisms and pathways in bladder cancer development and progression.

BACKGROUND: The basis for bladder cancer development and progression is complex and involves genetic abnormalities. These abnormalities yield phenotypic changes that allow normal transitional cells to become cancerous and finally acquire the "malignant phenotype." METHODS: The authors review the most common genetic alterations in bladder cancer and the molecular mechanisms and pathways involved in the conversion of normal transitional cell into malignant transitional cancer cells. RESULTS: There are several potential genetic changes of the urothelium that eventually cause bladder cancer initiation and tumor progression. Some of these alterations are also found in other malignancies suggesting that key common pathways exist in the development of cancer. CONCLUSIONS: As the roles of certain genes or proteins are further elucidated, a better understanding of cancer development can aid in the prevention, diagnosis, and treatment of bladder cancer.

Carcinoma, Transitional Cell↗
PubMedDate not supplied

Calcifying odontogenic cysts (keratoameloblatomas).

Two cases of calcifying odontogenic cyst were studied in males over 50. The histopathological diagnosis was based on the presence of ghost cells, partly calcified, in the thickness of the epithelium lining the cyst. These cells contained keratin occurring without keratohyalin granules. We consider that this lesion may be primary or secondary the latter occurring in common odontogenic cysts through the secondary differentiation of epithelial cells.

Humans↗