Search PubMed⌕ Search

Biomedical subjects

I Jonas

Publications and source records attributed to I Jonas.

At least 37 records · Page 2Linked to original sources

[The development of the nose following trauma in the growing stage].

In a longitudinal study, esthetic and functional sequelae after nasal fracture in 49 patients during the growth period had been analysed. The results were estimated according to the following criteria: extent of trauma, timing of trauma and mode of therapy. The sequelae of severe fractures were determined primarily by the extent of initial trauma. In case of minor trauma, the long-term results were influenced by age factor and mode of treatment. In adolescents good cosmetic results were obtained by restoration of the integrity of nasal structures. In infantile trauma, the realignment of the structures yielded good functional but poor cosmetic results. In untreated infants good cosmetic results were paid at the expense of insufficient nasal function.

Adolescent↗

A contribution to the pathogenesis of cholesteatoma. A histochemical and ultrastructural study.

In a histochemical and ultrastructural study the pathogenesis of cholesteatoma ostitis is analysed on human tissue. In the subepithelial layer there is evidence of an inflammatory reaction leading to proliferation of granulation tissue with bony invasion. Bony destruction is initiated by osteocytic osteolysis. In the case of cholesteatoma there is a combined action of extraosseous and osseous lysosomal enzymes. The pathological changes of the fibrillar elements suggest that the self-perpetuation of degeneration is maintained by a disturbance of fibrillogenesis. The causal pathogenesis of cholesteatoma formation is discussed as a function of a disturbance between cellular activity, extracellular matrix, and cellular surface.

Cholesteatoma↗

[On open nasal speech following operative procedures in the oro- and nasopharynx. A combined speech and cephalometric analysis (author's transl)].

A combined speech and cephalometric analysis was performed on 60 patients with class III malocclusion to evaluate the interaction between the cranio-facial skeleton and the disorder of an open nasal speech. There was an increase of durable open nasal speech after tonsillectomy but not after adenoidectomy. This predisposition to open nasal speech in class III patients appeared to be increased by the formation of the surrounding bony structures. In dependency to the cranio-facial morphology in the vertical dimension, the configuration of the bony nasopharynx and the sagittal jaw relationship were of significant importance. The cephalometric measurements confirmed the results of the speech analysis that the position and function of the soft palate are of essential significance for the development of an open nasal speech.

Adenoidectomy↗

[Cholesteatoma, oto- and tympanosclerosis: their general mechanism of tissue destruction (author's transl)].

The connective tissue contains extracellular enzymes for the turnover of the ground substance. If this enzyme system gets out of control there is development of a complex metabolic disturbance of all tissue components. The lysosomal dysfunction is the basis of the general mechanism of tissue destruction in cholesteatoma, oto- and tympanosclerosis. This process seems most enhanced in cholesteatoma. Emphasis is placed on the role of extracellular lysosomes (= matrix vesicles).

Cholesteatoma↗

[A study of spontaneous cure of sinusitis (author's transl)].

A clinical trial, in which the spontaneous self-cure rate of acute, chronic and childhood sinusitis was studied, is reported. The spontaneous cure rate in acute sinusitis, using analgesics only, range up to 79 per cent within 14 days. In chronic maxillary sinusitis using placebo treatment only, the pathological findings settled in 60.9 per cent within 21 days. A 5 year study of sinusitis in children aged 7-13 years showed a spontaneous self-cure rate of 94 per cent. These findings encourage a conservative approach in the management of sinusitis.

Adolescent↗

A contribution to the pathogenesis of otosclerosis.

In a histochemical and electron microscopical study the pathogenesis of otosclerosis was investigated. The morphological changes in the extra- and intracellular space indicated a complex metabolic disturbance of all tissue components. The observed chondrocytic chondrolysis stressed the role of the cartilage remnants in the otic capsule as an etiological factor. There was morphological evidence of a superimposed enzymatic defect.

Cartilage↗

[The effect of prognathism surgery on the temporomandibular joint. (A clinical and radiological evaluation of temporomandibular joint changes after various methods of surgery for prognathism)].

On the basis of clinical and roentgenologic examinations of progenia patients which were planned according to our occlusal concept and monitored postoperatively, we established that the condylar displacement in the roentgenogram offers an exact parameter for the extent of operative displacement of the condyles. Nevertheless, a direct conclusion concerning the clinical symptoms or freedom of complaints cannot be established on the basis of this roentgenographic analysis. The roentgenogram also showed considerable condylar alterations in patients with temporomandibular joint symptoms; greater displacement of the condyles was frequently demonstrable with temporomandibular joint complaints.

Humans↗

Relationship between tubal function, craniofacial morphology and disorder of deglutition.

26 children without hearing impairment have been examined by otolaryngologists and orthodontists. According to the tubal function test in a pressure chamber they were classifed into a group with good and poor tubal function. The E.N.T. examination was unconclusive for a possible relationship between rhinological findings, mode of breathing, sinusitis, size of tonsils, nasal airway resistance and tubal function. Adenoids proved to be a mechanical impairment for active tubal function as stated by many authors. The cephalometric analysis of lateral head films combined with a static and dynamic-functional evaluation of tongue posture revealed significant differences between children with good and poor tubal function. Subjects with a vertical craniofacial growth pattern seem to be predisposed for poor tubal function. Analysing static tongue posture in children with poor tubal function the tongue lies more retracted in a backward position. The back of the tongue is flattened in relation to the palatal arch. In children with good tubal function there is a much closer contact between the back of tongue and the hard palate. Subjects with poor tubal function have an increased incidence of abnormal deglutition combined with tongue-thrust, teeth-apart swallowing, lack of sealing off the anterior oral cavity and contraction of the circumoral musculature. In children with good tubal function one can find the somatic type of swallowing that means no contractions of the circumoral muscles, no tongue-thrust during deglutition but contact of the molars and contraction of the masseter muscle.

Airway Resistance↗

[Misleading x-ray diagnosis due to maxillary sinus asymmetries (author's transl)].

Asymmetries of the maxillary sinus with partial or total radiographic opacity mislead to the diagnosis of chronic sinusitis. Using three radiographic standard projections, computerised planimetric analysis and cephalometric studies helped to explain radiological opacity in 26 patients. So called "mucosal thickening" may be due to varying development of the zygomatic recess. Total opacity was caused not only by unilateral volume difference exceeding 30%, but also by straightning of the first lateral line in basal views of small and moderate sized sinuses. Cephalometric analysis in maxillary sinus asymmetry revealed ipsilateral transversal underdevelopment of facial- and skullbone. Reduced pneumatisation of the ethmoid, spenoid, mastoid and frontal sinus in diminishing order was also ipsilateral. Using photostat analysis there was nevertheless no correlation between facial- and coexisting maxillary sinus asymmetry.

Cephalometry↗

[The influence of training on the accuracy of roentgenographic cephalometric tracings (author's transl)].

The accuracy in landmark identification and in the determination of angular and linear measurements used in cephalometric analysis on lateral head film were statistically evaluated comparing operators with different levels of competence. The observed magnitude of methodological error was depending on - prior experience of the investigator - individual radiographic anatomical knowledge - rigour of landmark definition and - accuracy of the tracing procedure. Considering these sources of error some of the variability in the present investigation might be avoided by systematic instructions. In order to decrease the variation in landmark location the reproducibility of some points must be further improved by redefining them in their verbal assessments. From an educational point of view the correlation between individual radiographic anatomical knowledge and the magnitude of error in cephalometric analysis should be considered with particular emphasis.

Cephalometry↗