Search PubMed⌕ Search

Biomedical subjects

I Illés

Publications and source records attributed to I Illés.

11 recordsLinked to original sources

[Variabilities of kinetics of alcohol catabolism].

The resorption, distribution and elimination of ethanol vary individually. The differences in the resorption deficit and elimination coefficient can be of great extent. Though the generally accepted average of resorption deficit is 20%, which is calculated with in forensic practice, this value can occasionally be a lot higher. The elimination coefficient (beta value) depends on the blood alcohol level. Beta value was found higher than 0.15%o/h, the generally accepted one, even below 1.5% blood alcohol content, above 2.5% the beta value was found to be as high as 0.33%o h. This faster rate of ethanol clearance is due to induction of alcohol elimination systems. The ethanol metabolism at higher blood alcohol levels is characterized by Michaelis-Menten kinetics.

Alcohol Drinking↗

The combined use of transluminal angioplasty and selective clot lysis.

14 cases of transluminal angioplasty and selective clot lysis are reported. One patient removed the catheter before successful lysis and one lost his leg after an almost complete lysis due to advanced necrosis. Treatment was successful in the other 12 cases with complete or partial thrombolysis. Remaining clots were either smashed by catheter and/or successfully treated by oral fibrinolytic therapy. The injected dose of streptokinase was 5,000 U/h after an initial dose of 20,000 U in one hand injection. The duration of infusions was 6-72 hours. A total dose of 60,000-520,000 U streptokinase was adopted. Intraarterial infusion therapy was followed by long-term low-grade fibrinolytic treatment with oral penthosan polysulphate. Four bleedings at the puncture site, one epistaxis and a bleeding at the site of a recently extracted tooth were seen. Only one infusion was stopped due to moderate bleeding and without any drawback.

Angioplasty, Balloon↗