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Biomedical subjects

I Ia Kon'

Publications and source records attributed to I Ia Kon'.

At least 19 recordsLinked to original sources

[Moscow schoolchildren zinc status: correction of zinc insufficiency by organic zinc compounds].

The paper presents the results of study of zinc hair content in 43 Moscow schoolchildren, aged 9-11 years of both sex (May 2003 to December 2003). Significant drop of zinc hair content was established in 67% of schoolchildren. It was shown that the organic form of zinc enchanted zinc hair content. The findings will be used to implement preventive and health-promoting measures among schoolchildren.

Child↗

[The history of the development of the children nutritiology at the Institute of Nutrition of RAMS].

The history of infant and child nutrition department of the Institute of Nutrition of RAMS is briefly reviewed. The most important results of scientific investigations performed at the department from 1930 year till present time as well as methodical materials prepared by department specialists and serving as basis of official Ministry of Health recommendations and rules of infant and child nutrition, are discussed. Special attention is drawn to the problem of infant nutrition.

Academic Medical Centers↗

[Use of ketogenic diet in treatment of pharmacoresistant epilepsy].

Ketogenic diet (KD) is one of the most effective methods of epilepsy non-drug therapy. Ten patients with pharmacoresistant epilepsy, aged 1.5-18 years, were treated with individually matched and strictly controlled KD with high fat content and restricted amount of proteins and carbohydrates. After 1 year, only 4 patients kept the diet. Factors of efficacy, causes of withdrawal and side effects of KD are discussed.

Adolescent↗

[New way in dietotherapy of infants with food allergy].

The authors followed up (in outpatient conditions) a total of fifty 1-to-9-mounth-old infants with the diagnosis of atopic dermatitis, disseminated form, of subacute course. The infants were followed up for 3-12 months, with 83% of the 113 examined patients 1-3 weeks after the beginning of treatment having shown clinical improvement of cutaneous inflammatory processes. Of the 172 infants subjected to immunological examination, in 100--the level of total IgE in blood serum was significantly elevated. These children also had elevated level of the specific IgE antibodies to cow's milk proteins. The outcomes of the carried out dietotherapy using mixture "Nanny" showed that this therapeutic product resulted in remission in the majority of the followed up infants suffering from allergy to cow's milk proteins.

Animals↗

[Estimation of the allergenicity of specialized canned baby food made from fish, vegetables, and grains].

The influence of consumption of rations containing canned baby foods from mirror carp and Black Sea mullet on severity of system anaphylactic reaction to model food allergen in rats was studied and the level of antibodies to proteins of Black Sea mullet, mirror carp, Alaska Pollack, trout and big head was determined in serum of infants, suffering from food allergy through immune-enzyme analysis.

Allergens↗

[Biochemical methods for evaluating the nutritional status of children].

As the total system of the children's nutritional status evaluation is the necessary part in the children's health guarding measures complex the significance of biochemical methods as the part of this system have been analyzed in the article. On the base of the literature data as well as on the authors own experience the classification of the existing biochemical methods for more than 20 indices of children's nutritional status have been proposed. Advantages and disadvantages of the methods described have been briefly characterized.

Child↗

[Comparative study of the effects of different sour milk products on the intestinal microflora of healthy infants].

Our study was aimed to investigate in comparable conditions the composition of intestinal microflora of healthy infants who were given 9 types of fermented milk products. There were observed 103 practically healthy infants aged from 4 month to 1,5 years old. The obtained data have shown that studied products improve intestinal microflora in infants. Significant increase of bifidobacteria in infants intestines was promoted by fermented milk products containing alive bifidobacteria with rather high acidity. The most of products which contain bifidobacteria decreased the level of hemolisinproducing Escherichia coli and coagulase-positive staphylococcus. The products which not contain bifidobacteria decreased the level of Candida albicans and protei.

Age Factors↗

[5-hydroxymethylfurfural as indicator of quality of juices for child nutrition].

132 samples of domestic and imported juices and juice concentrates for child nutrition were analyzed on content of 5-hydroxymethylfurfurol (5-HMF), which is considered as an indicator of violation of juice manufacturing technology. The concentrations of 5-HMF in 15.9% of domestic juice samples and 10.3% of imported juice and concentrate samples were found higher than 20 mg/L--maximum level established by AIJN for some juices and nectars. The results confirmed the expediency of including of HMF maximum concentration in hygienic characterization of fruit juices and concentrates as an indicator of violation of their manufacturing and storage procedures.

Beverages↗

[Effects of characteristics of nutrition during the 1st year of life on some health indicators of young children].

Some health and development indicators were comparably analyzed at 218 children at age up to 3 years depending on the mode of feeding during first 12 month. The research was made at two stages. The first stage was done from 1990 till 1994. This period was characterized by so call traditional approach of the feeding system. The second one took place from 1995 till 1999. This period was characterized by new approach implementation such as free breast feeding, availability of modem infant formulas (adapted breast milk substitutes), changes at feeding system resulted to postponed because starting. The result of our research stated, that new approaches implementation at first year feeding system leaded to significant decreasing of the rate of the nutritional-depended diseases during the first year. Rates of incidence of acute-respiratory diseases, food allergy, functional stomach and gut-intestinal disorders low morphological indicators were depended on the way of feeding during the first 12 month. The differences hold on up to the end of the 3-d year. The results of research stated, that optimal health and development indicators were at breast feeding infants. Positive breast feeding long term influence depended of its duration, which must be at least for 6 month.

Age Factors↗

[Gastroesophageal reflux in nursing children: normal or pathology?].

We researched and analyzed how widespread regurgitation is among breast-fed and bottle-fed infants and the influence of regurgitation on their health later in life(up to age 3). We observed 146 infants. Sixty-eight percent regurgitated from 2 to 7 times a day. The highest regurgitation frequency was noted during the first three months of life. Regurgitation frequency then decreased. However it increased again at 4.5 to 5 months, about the time that solid foods were being added. We found that regurgitation frequency was higher in bottle-fed infants than in those who were breast-fed. After following these infants into their second and third years, we found that 5% of those 2-3-year olds who regurgitated as infants had gastro-intestinal disorders.

Bottle Feeding↗

[Importance of juices in nutrition of infants and preschool and school children].

The data on assortments and nutritional value of infant's juices are reviewed. Special attention is devoted to the disputable problem of the time when the juice is to be introduced to the infant diet. The necessity of further investigations on the quality criteria of juices for infant nutrition is emphasized. Modern data on nutritional value and physiological role of juices for preschool and school children are also presented. The perspectives of future investigations on the development and manufacture of new juices for infants and children are outlined.

Age Factors↗

[Effects of vitamin D metabolites on indicators of protein, phosphorus and calcium metabolism in children with chronic renal failure].

Amino acid analysis and investigation of nitrogen, calcium and phosphorus balance were done in two groups of patients with renal failure and osteodystrophy on vitamin D metabolites and analogues treatment. The results of the investigation confirm vitamin D metabolites influence on free amino acid metabolism and on nitrogen, calcium, phosphorus balance. We observed significant decreases of blood amino acids and good influence on renal osteodystrophy in patients treated with vitamin D metabolites. Vitamin D metabolites didn't influence retention, urinary and fecal excretion of endogenous nitrogen in patients with renal failure.

Adolescent↗

[Effect of vitamin D metabolites on the markers of protein, calcium and phosphorus turnover in children with chronic renal failure].

Amino acid analysis and investigation of nitrogen, calcium and phosphorus balance were done in two groups of the patients with renal failure and osteodystrophy on the Vitamin D metabolites and analogues treatment. The results of the investigation confirm vitamin D metabolites influence on free amino acid turnover and on nitrogen, calcium, phosphorus balance. We observed significant decreases of blood amino acids and good influence on renal osteodystrophy in patients treated with the vitamin D metabolites. Vitamin D metabolites didn't influence on the retention, urinary and fecal excretion of endogenous nitrogen in patients with renal failure.

Adolescent↗

[Proteolysis of immunoglobulins--biologically-active supplement in a fermented milk in gastrointestinal system of rats].

There was studied a possibility of immunochemical specificity conservation in immunoglobulins ingested with a bolus of experimental fermented milk formula. Adult rats received intragastrically 4 ml of studied formula supplied with gamma-globulin fraction of normal serum. Concentration was measured of IgG, IgA and IgM in gastric and intestinal content and in feces 1, 2 and 30 hours later the ingestion by radial immunodiffusion and ELISA. At two hours of digestion up to 25.7% of IgG could be recovered from gastrointestinal tract in immunoprecipitated form. IgA and IgM macromolecules degraded in the intestinal lumen with significantly higher rate. Only trace amounts of IgG were revealed in feces. Molecular weight of immunoprecipitated IgG in distal intestinal compartment was equal to 50 kD according gel filtration data. This corresponds to large breakdown fragments of Fab or Fc type. It was concluded that this fragments could stimulate in non-specific manner some kinds of immunocompetent lymphocytes of intestinal tract.

Animals↗

[Nutrition and health status of schoolchildren in Brianskaia region, residing in territories polluted by radionuclides].

Dietary intake, physical development and some indicator of health status of schoolchildren of Novosybkov (2th zone of strict control) and Vyshkov (3th zone) were studied. Energy and macronutrient intakes for schoolchildren can be considered adequate. Dietary intake intake of vitamins A, E, beta-carotene and especially C, and calcium were rather low. Low intakes of vitamin and calcium are results from low dietary consumption of milk and diary products, fruits and vegetables Physical development of Novosybkov's children is considered adequate and do not differ from that of Moscow's schoolchildren. The frequency of obese schoolchildren was seen in Novosybkov's children in comparison with Moscow's ones. On the contrary, among rural Vyshkov's children the high frequency of children with deficit of body mass was examined. The number of children relating to 2 or 3 groups of health was higher in Novosybkov than in Moscow. The data about higher prevalence of child morbidity were supported. One of risk factors of decreasing of children body toleration to low level of radiation are low level of vitamin intake and other defects of health nutrition.

Adolescent↗