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Biomedical subjects

I I Terskikh

Publications and source records attributed to I I Terskikh.

At least 19 recordsLinked to original sources
PubMed1992

[A comparative experimental study of pathogenic properties of new strains of California encephalitis virus serogroups].

Experiments in noninbred mice, Syrian hamsters and grey monkeys were made to characterize the pathogenic properties of new strain of the California encephalitis serogroup isolated for the first time on the island of Taimir, in the Murmansk, Leningrad, Tver regions and in Karelia. All the strains displayed marked tropism for the CNS. The strains isolated in the northern regions of this country turned out more pathogenic for the animals. The strain Leiv-12812 Kl (isolated in the Tver region) differed from the remaining ones in more pronounced pathogenicity for the monkeys, as well as in the site and intensity of brain lesions. The persistence of the virus in hamsters organs may play a role of a reservoir of infection in nature.

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PubMed1991

[Experimental infection caused by Issyk-Kul' arbovirus].

Experimentally in green monkeys, Syrian hamsters and white mice the authors studied the pathogenic properties of a new virus Issyk-Kul. The virus was determined in all animals--in blood and organs (brain, lungs, liver, spleen, kidneys). During the histological investigation the inflammatory and dystrophic injuries were established: in CNS, lungs, liver and kidneys. There was a distinct immunomorphological reaction in the spleen. The virus has pantropic properties and causes a generalized infection in animals.

Animals↗
PubMed1989

Biological profile of a virus belonging to California encephalitis complex isolated in Karelian Autonomous Soviet Socialist Republic.

We investigated in white mice and in Syrian hamsters the pathogenesis of infection with a virus belonging to the California encephalitis complex isolated in the Karelian Autonomous Soviet Socialist Republic. The pathogenic properties of the virus were investigated also in green monkeys. The localization and character of lesions in the organs of given animals appeared to be similar. The virus appeared to possess neurotropic activity, it propagated in the animal body by haematogenous route. The virus was found to be heat-resistant and pH-sensitive.

Animals↗