Biomedical subjects

I I Parilis

Publications and source records attributed to I I Parilis.

3 recordsLinked to original sources

PubMed1992

[Computer analysis and comparison of neurotoxin structures from snake and the anemone Radianthus macrodactylus].

Evolutionary trees of proteins analysed by means of computer comparative methods were reconstructed and the level of the structure and functional relationship was revealed. The distance between the percent amino acid contents was used to classify a group of toxins from the sea anemone Radianthus macrodactylus, which proved to belong to long neurotoxins. The scores were calculated by the pattern recognition method. By the use of the distance values, ten phospholipases A2 were divided into two groups, containing representatives of the most closely related organisms.

Amino Acids↗

PubMedDate not supplied

[Classification and identification of toxic polypeptides using a pattern recognition method].

A crucial rule for both rapid identification and classification of toxins by the relative content of the five most informative amino acids (glycine, cysteine, threonine, alanine and tryptophane) was established by using a computer algorithm of pattern recognition based on amino acid sequences of three families of toxic polypeptides.

Amino Acids↗

PubMedDate not supplied

[Determination of unique peptide fragments in nerve growth factors].

A new classificational method based on the availability of peptide fragments unique for a certain protein family is presented. Seven common peptide fragments unique for the nerve growth factor amino acid sequence are determined, and two of them are found in the neurotrophic factor from pig brain.

Amino Acid Sequence↗