Biomedical subjects
Publications and source records attributed to I I Kagan.
This article describes the method of quantitative estimation of computer tomograms, which served as the basis for description of morphometric and skeletotopic parameters of the pancreas and thyroid gland that were obtained as a result of study of 320 persons aged from 20 to 70 without pathology of these glands.
Individual differences of gastroduodenal transition shape, dimensions and structure were studied using histo-topographic preparations from 45 human cadavers, 60 intravital X-ray photographs and findings from 55 endoscopic examinations. The range of differences in the position of gastroduodenal mucosal junction on pyloric duodenal and gastric surfaces, was established. Muscular, muscular-submucosal and muscular-glandular types of gastroduodenal transition were distinguished. The morphological parameters of the differences of pyloric wall shape and dimensions were defined. Endoscopically, the dimension of pyloric orifice was classified as small, medium and large while its shape was described as round, oval, triangular or polygonal. Clinical applications of the data obtained were determined. Gastroduodenal transition is described as a complex, individually variable anatomical structure with clinically significant differences of its major structural components.
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The article presents the notions, contents and methods of studying microsurgical anatomy, which comprises macromicroscopic construction of an organ, biomechanic and morphometric characteristics of its structures, extraorgan macromicroscopic topography, intraorgan histotopography, macromicroscopic angio- and neuroarchitecture. The peculiarities of microsurgical anatomy of different organs and its clinical applications have been described.
Method of creation computer models of upper floor of abdomen organs: liver, gallbladder, duodenum, pancreas, stomach, blood vessels with using computer system "DUCT" was described. Details of modelled structures of the cylindric and complicated forms were noted.
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Linear parameters of corpus callosum and submucosal structures (transparent septum, cupula, thalamus, pineal body and the third ventricle choroid plexus) were measured using 80 MR tomograms and 40 craniograms of 20 patients aged 20-50. Linear parameters were compared with the cranium shape and statistically processed. The dependence of linear parameters of the structures mentioned upon the shape of the cranium was demonstrated. They were characterized morphometrically in dolychomeso- and brachiocephals. The data obtained are of interest in assessment of MR tomograms with pathological changes and individualization of surgical interventions in median structures of brain.
The morphology and distribution of the vascular changes in the brain and spinal cord, degrees and stages of the intracranial venous congestion course and morphology and dynamics of the venous haemorrhages were studied by means of clinico-sectional observations. Interrelations between vascular changes and anatomic structure were demonstrated so as the topography of the CNS venous bed.
By means of experimental material from 339 animals it was shown that microsurgical technique provides primary recovery of the wounds of the hollow organs, their anastomoses and blood vessels: demineralized bone is found to be a suitable material easily adapting in implantation. The use of microsurgical methods and technique and demineralized osseus matrix for nonosseous plastics is a perspective direction in improvement of the results of reconstructive and restorative operations on hollow organ and blood vessels.
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The experimental-morphological analysis covers the results of 62 operations for establishment of major vein anastomosis. In three series of experiments microsurgical suturing was used, while the control series employed the techniques of general surgery. In the microsurgery group, the best outcome (100 percent patency without anticoagulant administration) was achieved in cases when the venous anastomosis was protected by the demineralized tubular bone. Good outcomes were seen in cases with application of the original technique of mounting the venous anastomosis on rings of tubular bone. The advantages of microsurgical frame-mounted suturing of major veins over the general surgical techniques are demonstrated.
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As demonstrate chronic experiments performed in 36 rabbits after application of physical loadings having different intensity and duration, during the process of adaptation and deadaptation, there is a close interconnection between the changes in morphological signs and the physiological data. The most profound morphological changes appear in nontrained animals under a maximal loading up to "capacity" (especially in the hemisphere cortex). The dynamics of the adaptive reactions in the hemisphere cortex and in the hippocamp are not the same: the most profound adaptive rearrangements are observed in the cerebral hemisphere cortex. During the deadaptation, the morphological changes increase.
According to the authors data a secondary restoration of the lumen of a previously obstructed prothesis approaching a half of the initial diameter of the vein is not infrequent in the plasty of the main veins of a growing organism. This restoration results from pronounced processes of the recanalization of the intraprosthetic thrombus, which are observed in the plasty of the external jugular vein and anterior vena cava. It has been found that the recanalization occurs through the formation of some longitudinal canals in the thrombus. These canals join the capillaries growing through the pores of the prothesis which transform into venous vessels with the endothelial lining, vascular apparatus and directed blood flow,
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