Search PubMed⌕ Search

Biomedical subjects

I I Deriabin

Publications and source records attributed to I I Deriabin.

At least 19 recordsLinked to original sources
PubMed1988

[Status of the blood coagulation system in traumatic disease].

Under examination there were 198 patients with severe mechanical traumas at their admission to the clinic and on the 1st, 3d, 7th, 14th and 21st days by 25 hemocoagulation parameters determined by common present-day methods. The direction and degree of hemocoagulation alterations were found to be related with the severity of trauma, blood loss volume and severity of shock. It was shown that disseminated intravascular coagulation (DIC) of the II and III degree was developing in critical associated traumas, massive blood loss and severe shock in acute period of the disease. The acute form of DIC with reactive fibrinolysis was established in the lethal outcome during the shock period, latent (slow) DIC with local fibrinolysis took place in lethal outcomes in later periods.

Adolescent↗
PubMed1987

[Indications, methods and results of amputations of the extremities in isolated, multiple and associated traumas].

An analysis of 246 observations has shown that in patients with crushed extremities accompanied by shock the amputation is the most important antishock measure. The amputation performed by the method of primary surgical treatment of the wound is the method of choice. The amount of postoperative complications can be considerably reduced by using the primarily delayed suture, carbon sorbents on the stump wound, temporary immobilization of the extremity stump.

Adult↗
PubMed1987

[Characteristics of the pathogenesis of suppurative-septic complications of severe trauma].

The article analyzes results of examination of 261 patients with severe mechanical injuries. The examinations were performed at different periods after the trauma by biochemical and immunological methods. It was established that a number of indices (content of blood glucose, activity of aspartate aminotransferase, alanine aminotranspherase and T-lymphocyte content) were reliably different depending on the clinical course and the outcome of the trauma disease.

Adolescent↗
PubMed1987

[Potentials of infusion therapy in enhancing the detoxification effect of hemosorption in patients suffering from suppurative-septic complications of mechanical injury].

Under study was the application of microvasoplegia as a method of preoperative management in fulfilling hemosorption in patients with pyo-septic complications of a severe mechanical trauma. The method of infusion and medicamentous therapy used before hemosorption is described. Laboratory examinations of the enzyme toxemia level have shown pathogenetic grounds of the complex method of treatment. Positive clinical results were obtained.

Anti-Bacterial Agents↗
PubMed1985

[Immunological status and somatotropic activity of the pituitary in combined abdominal injuries complicated by peritonitis].

Associated injuries of the abdomen result in peritonitis twice more often than isolated ones, the peritonitis having more severe course and being the cause of lethal outcomes in 57% of the victims. The immune deficient state is thought to be one of the causes responsible for the reduced resistance to infection and the development of peritonitis in the postshock period. Patients with associated traumas show a considerable inhibition of the immune system within several hours and an impairment of its regulation which grows during the next day. So, even at the early terms the operative methods must be similar to those used in operations for the developed peritonitis.

Abdominal Injuries↗
PubMed1984

[Traumatic disease and metabolism].

The authors have established that the traumatic disease is accompanied by phasic nonspecific changes of metabolism correlating with the trauma severity as well as with its specific features and outcomes. Within the first 3-7 days catabolic processes are found to prevail and metabolic acidosis develop. Later, anabolic processes become activated in the non-complicated course of the disease. Normalization of most biochemical processes is accomplished within 15-21 days. More pronounced and prolonged disturbances of metabolism are observed in complications and lethal outcomes.

Acidosis↗
PubMed1984

[Correction of metabolic changes in preserved donor blood using hemosorbents].

The investigation of the effect of perfusion through the activated charcoal upon the biochemical and morphological parameters of the donor blood stored with the glucose-cytrate conservant during 14-21 days has shown normalization of the acid-base status, increased oxygen-transport function and energy balance of erythrocytes. So, blood continuously stored and purified with the help of sorbents is quite suitable for massive transfusions.

Acid-Base Equilibrium↗
PubMed1983

[Post-traumatic disease].

On the basis of an analysis of the many-years clinical examinations of patients with severe mechanical traumas the author suggests that the trauma disease be recognized as a special nosological unit including four different periods in its course, each of them requiring appropriate methods of treatment.

Cardiovascular System↗