[Chondrogenesis induced by autograft of the perichondrium in rabbits].
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Biomedical subjects
Publications and source records attributed to I Hirose.
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The experience of tooth extraction in four patients with sick sinus syndrome (SSS) is described, and electrocardiographic features and a guideline for dental extractions are discussed. Patients controlled by medical therapy were safely treated under administration of an effective drug prior to treatment, while patients with a cardiac pacemaker were examined and checked on the apparatus before tooth extraction by their own specialist. After freedom from the cardiac problems, dental extractions were done smoothly. Electrocardiographically, in the cases with pharmacological treatments, either normal sinus rhythm revealed after additional administration of isoproterenol, or more severe bradycardia-tachycardia pattern was shown immediately after tooth extraction. In the patients with a cardiac pacemaker, ECG presented patterns controlled by pacemaker but beats rose from their own sinus node in the anesthesia-extraction procedure with various grades.
Electron microscopic examination of a pigmented basal cell epithelioma of scrotal skin revealed many tumor cells and melanocytes which were laden with large packages of melanosomes. In tumor cells these packages were delimited by either single- or double-limiting membranes or were not membrane bound. The matrix of these large complexes was less electron dense and homogeneous than normal, containing electrontranslucent droplets besides melanosomes. No remnants of intracellular organelles such as nucleus, mitochondria or ribosomes could be found. The basal cell epithelioma cells in this case appear to have differentiated toward fetal basal cells and have developed the ability to phagocytize large packages of melanosomes.
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