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Biomedical subjects

I Hathorn

Publications and source records attributed to I Hathorn.

7 recordsLinked to original sources

Early detection of differences in surgical outcome for cleft lip and palate.

This study examined the dento-alveolar relationships of 5-year-old children born with a unilateral cleft lip and palate with primary surgical repair performed in one of two centres (Bristol or Oslo). The Bristol sample comprised 46 sets of study models and the Oslo CLP Growth Archive provided 54 cases with a very similar sex distribution. We used a recently developed 5-year-old index to measure differences in outcome between the two centres. The Oslo sample were assessed as having up to 57 per cent in the ideal groupings (1 and 2), in the Bristol group this was only 35 per cent. Bristol had up to 46 per cent of cases assessed in the worst groups (4 and 5). The comparative figure from the Oslo group was 15 per cent. These results suggest that it is possible to detect differences in surgical outcome at 5 years of age.

Age Factors↗

Study models of 5 year old children as predictors of surgical outcome in unilateral cleft lip and palate.

This study examined features of dental occlusion in patients born with a unilateral cleft lip and palate (UCLP). The intention was to develop a 'Goslon type' index for 5 year old children. The Goslon ranking system was used on longitudinal study models taken at 5 and 10 years of age of the same patients. All patients had UCLP and this had been repaired using a Millard type lip repair and a Veau Wardill or Von Langenbeck palatal closure. There was good intra-examiner agreement for ascribing 5 and 10 year old models to one of five categories (excellent-very poor). Inter-examiner agreement on both sets of models was at worst moderate. Two of the examiners identified up to 93 per cent of 5 year old models which either remained in the same category or deteriorated by 10 years of age. At worse the results demonstrated 70 per cent of cases of 5 years of age remained in the same category or deteriorated by 10 years of age. Consensus agreement has produced five categories of outcome for these 5 year old models. This new index is to be subjected to further validation. This study has therefore provided, for the first time, a mechanism for assessing the results of CLP surgery earlier than indices already available.

Child↗

Facial growth in patients with unilateral clefts of the lip and palate: a two-center study.

Two groups of 10-year-old patients with complete unilateral clefts of the lip and palate were examined in this study. Two centers; Bristol, U.K. and Oslo, Norway, who had different treatment regimens were used. The groups comprised 40 patients from Oslo and 32 from Bristol. The groups were matched, in proportion to the size of the groups, for age, sex, and presence of Simonart's bands. In Oslo, a Millard lip repaired was performed at 3 months of age with a von Langenbeck palatal repair at 18 months, no presurgical orthopedics was employed and there was no primary nasal correction. The Bristol center also repaired the lip at 3 months with a Millard type repair but also performed a radical nasal correction at the same time. The palate was repaired at 6 months with a Veau repair, and presurgical orthopedics using a pinned arch orthopedic plate was carried out. In addition, the volume of primary repairs per surgeon was much higher in Oslo, and a much stricter treatment protocol was used compared with Bristol. Lateral cephalograms obtained within 1 year of the child's tenth birthday were digitized, and the craniofacial morphology of the two groups was compared. Significant differences in maxillary growth and soft tissue profile were noted with a much more retruded mid-face and flatter nasiolabial angle in the Bristol group. The main factors for the better results in Oslo are suggested to be the absence of presurgical orthopedics, no radical nasal correction, the high volume of operations performed per surgeon, and the stricter protocol.

Age Factors↗

The Goslon yardstick applied to a consecutive series of patients with unilateral clefts of the lip and palate.

First described in 1987, the Goslon yardstick has been used since as a reliable and reproducible means of measuring dental arch relationships and, therefore, the quality of facial growth. The dental study models of a group of 32 consecutively treated patients with unilateral clefts of lip and palate, from the Frenchay Hospital, Bristol, U.K., were analyzed using the Goslon yardstick. More than 50% of the sample were in the unfavorable Goslon groups IV and V. Because of these results, we at Frenchay Hospital now base our related surgical procedures on the early vomerine closure of the anterior hard palate without nasal or alveolar repair at 3 months, followed by primary hard and soft palate closure at 6 months.

Age Factors↗

Holograms as substitutes for orthodontic study casts: a pilot clinical trial.

A pilot study of holograms as substitutes for study casts during routine clinical treatment was carried out by four clinicians on 56 patients over a 6-month period. Three of the clinicians found holograms to be as informative as study casts and equally or more convenient, but one clinician considered holograms to be inferior to study casts in both these respects. In addition, replicate quantification of malocclusions by means of the Summers index showed very similar rates of random error for holograms and for study casts and no significant systematic error between the scores obtained. Currently available holograms merit further investigation as alternatives to study casts. Refinement to further improve the convenience, informativeness, and economy of the holograms is also being undertaken.

Holography↗

Historical note.

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