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Biomedical subjects

I Harris

Publications and source records attributed to I Harris.

At least 37 records · Page 2Linked to original sources
PubMed1993

Determination of L-methionine-dl-sulphoxide in tissue extracts.

The amino acid fraction from rat liver, heart and skeletal muscle was prepared by the separation of sulphosalicylic acid extract on Dowex 50 H+ form. The presence of L-methionine-dl-sulphoxide in these extracts was identified and compared by three independent chromatographic methods: ion-exchange, Pico-Tag and reversed-phase high-performance liquid chromatography after precolumn derivatisation with diethylethoxymethylenemalonate. Quantitative data indicate that L-methionine-dl-sulphoxide is present in the intracellular pool at the levels of free methionine.

Animals↗
PubMed1993

Effect of the immediate precursors of phenylalanine and tyrosine on growth and protein synthesis in phenylalanine- and tyrosine-deprived HeLa cells.

Although Phe is an essential amino acid in mammalian cells, its immediate precursor, beta-phenylpyruvic acid (BPP), when present in Phe-deficient medium at 10(-4) and 10(-3) M is converted at a sufficient rate to Phe to sustain growth at 60 and 100% of non-deficient control HeLa S-3 cells, respectively. In contrast, Tyr-deficient cells were unable to convert the immediate precursor of Tyr, OH-beta-phenylpyruvic acid (OHBPP), nor could BPP rescue Tyr-deficient cells. The results are considered in terms of the organization of intracellular pathways by which precursors are transaminated and made available for protein synthesis.

Cell Division↗
PubMed1992

Faculty evaluation of student performance: a step toward improving the process.

Most clerkship evaluation systems give the greatest evaluative weight in deriving grades to some form of evaluation by faculty and housestaff, although few studies have been reported concerning which elements of performance are most important or which discriminate best. The results of this study show that a select group of faculty, heavily involved with assessment of student performance, agreed that certain aspects of performance were more important and/or discriminated better between average and superior medicine clerks. We suggest that those aspects of performance be given more consideration when designing curricula, providing student feedback, and assigning grades for medicine clerkships and that medical educators engage faculty and housestaff in the formal discussion of issues surrounding evaluation.

Clinical Clerkship↗
PubMed1992

Urea synthesis in rats fed diet containing kidney beans.

When rats were fed a diet containing kidney bean (Phaesolus vulgaris) urea excretion was increased 3-5 fold. Isolated liver mitochondria from rats fed the kidney bean diet produced 40% more citrulline in the presence of arginine than mitochondria isolated from control rats. Mitochondrial activities of urea cycle enzymes and N-acetylglutamate synthetase were similar in animals fed diets containing kidney bean or lactalbumin. The possible mechanisms causing acute urea production in rats fed with kidney bean are discussed.

Acetyltransferases↗
PubMed1991

Is the coned lateral lumbosacral junction radiograph necessary for radiological diagnosis?

The lumbar spine radiographs of 400 orthopaedic outpatients were reviewed to determine if the absence of the coned lateral lumbosacral junction radiograph would lead to a loss in diagnostic accuracy. In 84 (21%) patients the antero-posterior and lateral lumbar spine radiographs failed to visualize adequately the lumbosacral junction. In these patients the coned lateral lumbosacral junction radiograph resulted in 17 (4.5%) diagnoses which would otherwise have been missed. The diagnoses were spondylosis (11), spondylolisthesis (3), spondylolysis (1), Paget's disease (1) and infection (1). Absence of the coned lateral lumbosacral radiograph will result in inadequate demonstration of the lumbosacral junction and a loss in diagnostic accuracy.

Humans↗
PubMed1990

Influences of marital status and parental status on the professional choices of physicians about to enter practice.

The trend toward increasing numbers of working women may alter the ways both men and women physicians structure their professional lives. The 1987 graduates of residency and fellowship programs at the University of Minnesota Medical School--Minneapolis were surveyed in June 1987 about professional plans and factors that led to their decisions. The women expected that their spouses would contribute half of their family's income, whereas the men expected that they would be largely responsible for their family's income. The married women with children planned on working fewer hours than did other physicians. Family structure may play an important role in preventing the convergence of men and women physicians' personal incomes or working hours.

Career Choice↗
PubMed1989

Benign cholangioma of the liver.

The ultrasonic, computed tomographic, magnetic resonance and angiographic appearances of a case of benign cholangioma of the liver are presented. They have not been previously described.

Adenoma, Bile Duct↗
PubMed1984

Professionalism among nurse educators.

Three hundred seventy nurse educators who teach in a midwestern state in nursing education programs participated in a mailed survey to investigate the relationship of educational preparation of faculty to their attitude on professionalism. Hall's 25-item Professional Scale was used to measure the dependent variables of autonomy, use of the professional organization as a major referrant , belief in the public service nature of nursing, belief in self-regulation and sense of calling to the field, and the independent variable educational preparation of the nursing faculty member. There were very few significant differences among nurse educators when grouped according to highest level of education. Mean scores on the attitudinal components of professionalism, however, illustrated a consistent pattern of the higher the educational preparation, the higher the attitudes on professionalism. Implications for further study are discussed.

Analysis of Variance↗
PubMed1979

Learning style in a primary care internal medicine residency program.

Individual differences in learning style should be one factor that is considered in medical education program planning and instruction, and this can be accomplished by using Kolb's learning style inventory (LSI) in a primary care internal medicine residency program. Case accounts are presented to suggest how the LSI can be used to enrich teaching-learning encounters. To our knowledge, these case accounts are the first reports of an important use of knowledge about learning style, obtained through instruments such as the LSI. Other educational applications are suggested with respect to evaluation formats and choice of instructional methods.

Faculty, Medical↗