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Biomedical subjects

I Hara

Publications and source records attributed to I Hara.

At least 271 records · Page 15Linked to original sources
PubMed1976

Antibody like activities against cholesterol ester in anti-LDL antiserum. An observation on the surface of LDL.

The antibody like activities against cholesterol and cholesterol ester were examined by means of radioimmunoassay system, immunolysis of liposomes containing cholesterol and other steroids. In comparison with anti-etiocholenic acid antiserum and anti-cholesterol succinate antiserum, it was proved that anti-LDL antiserum contained 2 kinds of antibodies, one was specific to the structure of cholesterol skeleton and other was specific to the whole structure of cholesterol ester. LDL only combined with anti-cholesterol succinate antibody resulting with the inhibition of the interaction between sheep red cell sensitized by cholesterol succinate and anti-cholesterol succinate antiserum by means of passive hemagglutionation reaction.

Animals↗
PubMed1976

Solubility of phosphatidylcholine in chloroform. Formation of hydrogen bonding between phosphatidylcholine and chloroform.

The solubility of phosphatidylcholine (PC) was studied by the spectroscopic analysis and the measurement of the solubility. The qualitative analysis of infrared absorption spectra confirmed the existence of two types of hydrogen bondings between chloroform and PC, one between chloroform and the C=O group of PC and the other between chloroform and the phosphorylcholine group of PC. The quantitative analysis of the C-D stretching vibration bands of the chloroform-d solution of PC showed that the latter hydrogen bonding mainly contributes to the solubility and that PC dissolves in chloroform to form a complex consisting of a few or more molecules of chloroform and one molecule of PC. We discussed in this report about the molecular organization of PC in chloroform solution.

Chloroform↗
PubMed1976

Preparation of anti-etiocholenic acid antiserum and anti-cholesterol succinate antiserum and their cross reactivities.

Anti-3-hydroxy 5-androstene carbonic acid (etiocholenic acid) antiserum was obtained by immunizing rabbits with anetiocholenic acid-polylysine complex. Anticholesterol succinate antiserum was also prepared by immunizing rabbits with a cholesterol succinate-polylysine complex. The cross reactivities of these antisera were examined by means of radioimmunoassay system, immunolysis of liposome and passive hemagglutination reaction. Anti-etiocholenic acid antiserum was specific against the structure of ring A of cholesterol and the nature of OH group at C3 position and anti-cholesterol succinate antiserum was specific against the side chain similar to that of cholesterol.

Androstenols↗