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Biomedical subjects

I H PAGE

Publications and source records attributed to I H PAGE.

At least 37 records · Page 2Linked to original sources
PubMed1963

RENAL BAROCEPTOR CONTROL OF RENIN SECRETION.

Small reductions in renal perfusion pressure to levels still within a physiologic range, which did not reduce renal blood flow, caused the kidney to release renin. Renin appeared in much larger amounts in renal-vein blood than in renal lymph. Release of reruin appears to be mediated by a renal baroceptor rather than by ischemia.

Angiotensins↗
PubMed1963

Angiotensinase with a high degree of specificity in plasma and red cells.

A peptidase with a high degree of specificity for angiotensin II occurs in normal human plasma and red cells. Preparations from both sources have the same pH optimum, require calcium ions, and hydrolyze valyl(5)- or isoleucyl(5)-angiotensin II, but do not hydrolyze beta-aspartyl(1)-angiotensin II, arginyl(1)-angiotensin II or deaminoangiotensin II. This enzyme, given the name angiotensinase A, requires alpha-L-aspartic acid or alpha-L-asparagine as the N-terminal amino acid in its angiotensin substrate, and thus differs from kidney leucine aminopeptidase. Other peptidases known to hydrolyze angiotensin also hydrolyze at least one of the other angiotensin analogs with substitution in the one position.

Angiotensin II↗