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Biomedical subjects

I H Bernstein

Publications and source records attributed to I H Bernstein.

At least 19 recordsLinked to original sources
PubMed1999

Pharmacist recognition of potential drug interactions.

The ability of pharmacists to identify potential drug interactions was studied. Simulated medication profiles were created from a list of 16 drugs. Staff pharmacists and soon-to-graduate student pharmacists at a Veterans Affairs medical center each received a set of eight 2-drug profiles, four 4-drug profiles, two 8-drug profiles, and one 16-drug profile. Each set of profiles contained a number of pairs of drugs rated by the Drug Therapy Screening System as producing an interaction of moderate or major importance. The subjects were given one hour to screen the profile for the potentially interacting pairs. The subjects detected only 66% of the interactions in the 2-drug profiles, 34% of the interactions in the 4-drug profiles, 20% of the interactions in the 8-drug profiles, and 17% of the interactions in the 16-drug profile. None of the subjects detected all interactions in the 8- or 16-drug profiles. Both true-positive and false-positive rates of identification decreased significantly as the number of drugs listed on the profile increased. This primarily reflected a reduced tendency to report the presence of drug interactions, but there was additional evidence that the accuracy of identification also declined. The number of years of pharmacy training was the only demographic characteristic highly correlated with accuracy. More years of pharmacy education seemed to improve the ability to detect drug interactions. However, none of the pharmacists or students was able to detect all potentially interacting pairs in a profile containing 8 or 16 drugs. Computerized drug interaction profiles should be used by pharmacists to ensure recognition of all potential drug interactions.

Drug Interactions↗
PubMed1997

On the dimensionality of the Buss/Perry Aggression Questionnaire.

Buss and Perry (1992, Personality and Social Psychology, 63, 452-459) developed a 29-item test that presumably measures four aggression-related dimensions (physical aggression, verbal aggression, hostility, and anger). This study examined the factor structure of the items with particular concern towards seeing how much of the structure previously noted was an artifact of differences in item distributions. Although the scales are intercorrelated to the point that they may not span four dimensions, the scales are in fact multivariate in that the structure is not an artifact of differences in item distributions found with other presumed multifactor scales.

Adult↗
PubMed1995

On the utility of the West Haven-Yale Multidimensional Pain Inventory.

STUDY DESIGN: Two studies evaluated the West Haven-Yale Multidimensional Pain Inventory. This 52-item inventory contains 12 scales divided into 3 parts: 1) interference, support, pain severity, self-control, and negative mood; 2) punishing responses, solicitous responses, and distracting responses; and 3) household chores, outdoor work, activities away from home, and social activities. OBJECTIVES: The objective of study 1 was to investigate the internal structure of the Multidimensional Pain Inventory and its demographic correlates. The objective of study 2 was to explore its external correlates (construct validity). SUMMARY OF BACKGROUND DATA: The Multidimensional Pain Inventory appears promising because of its brevity, scope, ease of administration, and initial results. Despite this, it has attracted very little attention in the orthopedic literature since its introduction nearly a decade ago. METHOD: The internal structure was examined using oblique multiple group confirmatory factor analysis. Demographic correlates were examined using discriminant analysis. The external correlates were examined using multiple regression and discriminant analysis. RESULTS: The items' proposed structure fit well except that two pairs of scales are poorly separated: 1) activities away from home and social activities, and 2) solicitous responses and distracting responses. Correlations with external criteria are meaningful. CONCLUSIONS: The Multidimensional Pain Inventory meets standards of reliability and convergent validity, and it may be an improvement over current psychometric devices used to this same end.

Black or African American↗
PubMed1994

On the utility of the SCL-90-R with low-back pain patients.

The SCL-90-R has become an increasingly popular measure of maladjustment. Its use beyond simply screening chronic low-back pain (CLBP) patients has been criticized, however, in part, because it appears to be a single-factor instrument. In fact, its nine major scales do share only one important common factor, i.e., general psychological discomfort. The scale most applicable to CLBP, however, somatization (SOM), has sufficient specific variance that it does not simply measure discomfort and predicts several other measures better than the SCL-90-Rs more reliable composite measure (GSI). Using SOM in conjunction with the GSI to separate psychological from physical discomfort is therefore both clinically and psychometrically appropriate. Other objections to the test are critically evaluated. The potential clinical relevance of the SCL-90-R is discussed.

Adaptation, Psychological↗
PubMed1993

Concurrent processes: the affect-cognition relationship within the context of the "mere exposure" phenomenon.

The affect-cognition relationship and Zajonc's (1968) "mere exposure" hypothesis were examined in two studies that involved ratings of: (1) preference and familiarity for geometric forms previously scaled for complexity and (2) preference or height and familiarity for male yearbook pictures previously scaled for attractiveness or height. Two exceptions to his hypothesis were noted: simple geometric forms and unattractive faces showed satiation, and faces seen once before were rated more attractive than both novel faces and faces seen twice before. Moreover, mere exposure effects were noted with a nonaffective dimension (height). The major finding was that presentation frequency generally manifested independent relations to affect and rated familiarity, as well as to height and rated familiarity, therefore evoking a concurrent response process (Eriksen, 1960).

Affect↗
PubMed1991

Reexamination of Eisen, Zellman, and McAlister's Health Belief Model questionnaire.

Eisen, Zellman, and McAlister proposed a 22-item scale to measure four Health Belief Model (HBM) constructs as applied to adolescent contraceptive behavior. Their factor analysis led them to conclude that there were several discrepancies in their proposed scales. We suggest that they were unduly pessimistic. Although their proposed scales could stand improvement, they are adequate preliminary tools. The major reason they concluded that the scales were deficient was that they applied criteria that are generally appropriate for continuous data to their inherently discrete (categorical) item response data. A secondary consideration is that confirmatory methods of factor analysis can yield results that bear more directly on their proposed organization of items than the traditional exploratory methods that they used. A reanalysis of their data suggests that their proposed scales have fewer problems than they believed they had. Our results increase the likelihood of standardizing HBM measures.

Adolescent↗
PubMed1990

Perceptual and response interactions in semantic priming.

In two experiments, subjects made pairs of lexical decisions verbally. In Experiment 1, masked stimuli appeared concurrently to the left and right of fixation; in Experiment 2, nonmasked stimuli appeared sequentially at fixation. The left-hand letter strings were judged more accurately in in Experiment 1, and the second letter strings were judged more accurately in Experiment 2. Each string in the pair could be either a word (e.g., fork) or a nonword anagram (e.g., frok). Consequently, the two strings in the pair could be related (e.g., fork-spoon, frok-spoon, etc.) or unrelated (e.g., fork-door, frok-door, etc.), independently of whether neither, either, or both strings were words. Semantically related stimuli induced consistent biases to respond "word," as noted in other studies. These biases were typically stronger for the event reported second. Minimal evidence was found for perceptual priming effects. The asymmetrical effects were consistent with spreading-activation-type mechanisms, but other considerations support a multiple-process view.

Adult↗
PubMed1989

Cognitive biases and depression.

Compared symptomatically depressed, clinically remitted, and normal controls using cognitive measures designed to be traitlike and statelike in cross-sectional and longitudinal designs, respectively. Remitted depressives and normal subjects did not differ in their attributional biases, endorsement of dysfunctional attitudes, or interpretation of schema-relevant ambiguous events, but both groups differed from symptomatic depressives. Depressive episodes thus affect cognition, but cognitions measured by self-reports are more statelike than traitlike.

Adolescent↗
PubMed1989

Semantic priming: subliminal perception or context?

Briefly presented, masked priming stimuli that cannot be identified by themselves can affect the processing of subsequent targets. The effect, which is sometimes viewed as a demonstration of unconscious processing, has been linked to the subliminal perception literature. Experiments 1 and 2 indicated that the identification of primes in the context of semantically related targets is superior to the identification of primes presented alone, and that the identification of primes in the context of semantically unrelated targets is inferior to the identification of primes presented alone. Experiment 3 indicated parallel findings in a recognition task. Consequently, an explanation of semantic priming in terms of the interactive nature of stimuli that are near to one another in time seems preferable to one based upon concepts of unconscious processing and subliminal perception.

Adult↗
PubMed1987

Invariance in the MMPI's component structure.

Bernstein and Garbin (1985b) suggested that the Minnesota Multiphasic Personality Inventory's major clinical scales (excluding Scales ? and 5) can be approximated by an oblique three-component structure: (a) Profile Elevation, (b) Test-taking Attitudes, and (c) Optimism-Pessimism, collectively termed the salient weight model. In this study, we found that both this model and the MMPI's principal component structure remain invariant across race, sex, and, as previously noted, context of testing (job applicants vs. inmates in correctional institutions). We further noted that several alternative definitions of Profile Elevation provide equally satisfactory representation of the relations among the scales. This factor invariance is necessary, but not sufficient, for the MMPI to be viewed as unbiased.

Adult↗
PubMed1981

Contrast sensitivities through spectacles and soft contact lenses.

Contrast sensitivity function (CSF) measurements were made on nine subjects who wore a spectacle lens on one eye and a soft contact lens on the other eye continuously for 18 hr. The functions were the same for the two types of correction and did not become worse over time. Contrary to an earlier report by Applegate and Massof (1975), there was no evidence of a visual decrement caused by the wearing of soft contact lenses or from the moderately prolonged use of a contact lens. A major difference between our study and theirs was that none of our subjects had more than 0.12 D of astigmatism, whereas their soft contact lens subjects had from 0.75 to 1.00 D of astigmatism. Thus, impairments that were previously noted by soft lens wearers may be limited to astigmatic subjects. In addition, no evidence was found that occasional 18-hr use of soft contact lenses has any measurable, immediate effects on visual acuity as inferred from contrast thresholds.

Adolescent↗