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Biomedical subjects

I Goldiamond

Publications and source records attributed to I Goldiamond.

5 recordsLinked to original sources

Schedule-induced defecation.

Excessive defecation, typically considered to be a concomitant of stress, was experimentally induced or eliminated under specific schedules of positive reinforcement of lever pressing by rats. The schedules were, by and large, those under which polydipsia is typically induced. In the first of three experiments, rats under fixed-interval 32-second schedules and variable interval 32-second schedules for food and water reinforcers defecated profusely, but not under fixed-interval one-second schedules or other small interval schedules. Somewhat higher rates of defecation were observed on variable interval 32-second schedules than on fixed-interval 32-second schedules. In a second experiment, fixed-ratio schedules were used, some of which resulted in responding such that reinforcement densities were similar to those on the interval schedules that induced defecation. Defecation was not systematically induced by these ratio schedules. In a third experiment, fixed-time schedules of food presentations were utilized. High rates of defecation were induced comparable to those induced by interval schedules of the same time parameter. No other behavior commonly termed "emotional" was observed in any of these experiments.

Animals

Modification of human gastric acid secretion with operant-conditioning procedures.

In an attempt to control gastric acid secretion with operant-conditioning techniques, four normal women were given visual feedback on gastric pH plus money reinforcers. When money was made dependent on increased secretion in a differential-reinforcement-of-high-rates schedule, the rate of secretion of three of the four subjects increased to three times baseline. When money was then made dependent on decreased secretion in a differential-reinforcement-of-other-behaviors schedule, the rate of secretion of these three subjects returned to baseline levels. Heart rate, respiratory frequency, abdominal electromyographic activity, and stomach motility (measured by the electrogastrogram method) were not consistently correlated with acid secretion across subjects, although individual subjects showed substantial correlations between acid secretion and one or more other physiological response.

Adult

Some discriminative properties of fixed ratio performance in the pigeon.

The discriminative control over a spatial choice response exercised by prior behavior was studied using a procedure involving discrete exposures to a two-member chained schedule. The initial member (red key) was either a smaller or larger fixed ratio (Mix FR:FR), the completion of which produced, after a 1-sec delay, two white response keys. If the larger FR had been completed as the initial chain member, a single peck on the right white key was reinforced; after the smaller FR, a peck on the left white key was reinforced. Frequencies of unreinforced responses (S(Delta) responses) were determined with several pairs of red-key FRs: 95-5, 75-25, 65-35, 60-40, 58-42 and 50-50. The S(Delta) response frequencies were low through the FR pair 65-35; sharp increases were obtained with pairs 60-40 and 58-42. Later, curves analogous to stimulus generalization functions were obtained using a probe procedure. Finally, the delay interval between completion of a red-key FR and the white-key choice response was manipulated: results were variable, but S(Delta) response frequencies tended to increase with increasing delays.

Animals