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Biomedical subjects

I Georgiev

Publications and source records attributed to I Georgiev.

30 records · Page 2Linked to original sources
PubMed1981

[Serum enzyme dynamics in progressive muscular dystrophies].

The activity of serum enzymes, such as, creatine kinase (CK), pyruvate kinase (PK), aldolase (ALD), lactate dehydrogenase (LDH), sorbitol dehydrogenase (SbDH), malate dehydrogenase (MDH), glutamate-aspartate aminotransferase (AST), glutamate-alanine aminotransferase (ALT), myokinase (MK), glucosephosphate isomerase (GPI), alkaline phosphatase (AlkP), pseudocholinesterase (PsCHE) isocitrate dehydrogenase and gamma-glutamyltranspeptidase (gamma-GTP), was determined in 256 patients with progressing myodystrophy (PMD) (Duchenne's form in 125, Becker's form in 14, pelvicohumeral form in 36, humeroscapulofacial form in 19, ocular form in 10, other rare forms in 34, and nonidentified forms in 13 patients). In the control group (64 men, 56 women and 50 children), the activity of the enzymes was found to depend on the patients' sex and age. With regard to both parameters, i. e. the degree of the enzyme activity rise and the frequency of the pathological values the most informative were CK, then PK and ALD, and then all the other enzymes. Of all the PMD forms the enzymatic activity appeared to be the highest in patients with the pseudohypertrophic malignant form. By determining the activity of five enzymes (CK, ALD, LDH, AST and ALT) and taking into consideration the patient's age, the onset and the duration of the disease one can distinguish between sick and healthy subjects, as well as between various forms of PMD.

Adolescent↗
PubMed1979

[Malignant tumor originating from the interstitial cells of the testis (leydigoma)].

The authors describe a very rare and very interesting case of malignant tumour, originating from the interstitial cells of the testis, developed in a male of 53, with multiple metastases. The patient developed chronic hypocorticism, owing to bilateral metastases in adrenal glands and finally followed by an Addison coma. The case is of interest because no data are available in literature about metastases in adrenals with and adrenal insufficiency advancement.

Acute Kidney Injury↗
PubMed1977

[Treatment of hypertension with the preparation Tendor].

The hypertensive preparation "Tendor" of the Hungarian firm "Chinoin" was applied in the treatment at the Clinic of Propaedeutics of Internal Diseases. For the period from 1975-1977, 28 hospital patients and 8 out-patient department department patients with essential hypertension were followed up. Especially good effect was obtained among the patients in II and II stage with light and moderate hypertension degree among the group followed up. The favourable effect of the preparation is manifested as early as the first 10-12 days after treatment, without the combination of "Tendor" with some other hypotensive remedies.

Adult↗