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Biomedical subjects

I Gedalia

Publications and source records attributed to I Gedalia.

At least 109 records · Page 6Linked to original sources

The effect of fluoride alone or fluoride followed by calcium and vitamin D on disuse osteoporosis of the rat tail vertebrae.

The therapeutic effect of fluoride alone or fluoride followed by calcium and vitamin D administration on the osteoporosis induced by immobilization of the rat tail vertebrae was investigated. Tail immobilization was carried out by musclectomy and tendectomy. After 60 days of immobilization, the vertebrae were examined for bone mass, breaking strength, ash percentage and Ca, P and F content. NaF or Ca and vitamin D as separate treatments improved the osteoporosis induced by immobilization. The effects of NaF treatment were more pronounced than those of Ca and vitamin D. NaF and NaF followed by Ca and vitamin D produced a similar degree of improvement in breaking strength. The fact that fluoride and calcium and vitamin D were administered separately and sequentially may explain the absence of a synergistic effect.

Animals↗

The effectiveness of sodium fluoride treatment with and without iontophoresis on the reduction of hypersensitive dentin.

The effectiveness of topical sodium fluoride applied with and without iontophoresis was compared in patients complaining of tooth hypersensitivity. Reduction of sensitivity to cold and mechanical stimuli was evaluated during a period of 8 months by pain scoring in the exposed cervical dentin of homologous teeth on the two sides of the jaws. There was a significant decrease in the sensitivity of the exposed cervical dentin after treatment with sodium fluoride solution, with or without iontophoresis, during the whole experimental period. There was no striking difference between the two forms of treatment with respect to the reduction of sensitivity to mechanical and cold stimuli.

Adult↗