[Current theories on the methods of stimulating the ovulation in hypogonadotropic amenorrhea].
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Biomedical subjects
Publications and source records attributed to I G Torganova.
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A comparative assessment of variations in sex hormone levels and echographic parameters of fertile and infertile cycles was carried out in patients with gonadotrophic deficiency during pergonal induction of the ovulation. It was demonstrated that 83% of the infertile cycles were the first stimulation cycles. Basic differences were identified in the variation of sex hormone levels and echographic parameters of target organs between the fertile and infertile cycles. It is concluded that the first ovulation-induction course should be regarded as a preventive or preparatory one, where an optimum drug dosage is adjusted while the gonads and target organs are getting ready for the ovulation.
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A multiple correlative analysis of the relationship between the follicle size, steroid hormone concentration in the follicular fluid and their peripheral blood content during different stages of the follicle growth was performed. It was suggested that both the growth of dominant follicle and the change in steroid hormone concentration are non-linear processes. It was demonstrated that steroid hormone content in the peripheral blood reflects steroidogenic activity of the dominant follicle thecal tissue.
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