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Biomedical subjects

I G Popescu

Publications and source records attributed to I G Popescu.

At least 37 records · Page 2Linked to original sources

Is rehabilitation of patients with chronic bronchial asthma possible.

Based on his own experience and on the data in the literature the author considers that rehabilitation of adults with chronic bronchial asthma is possible at any stage of disease if there are no complications or morbid associations to prevent it. Rehabilitation of chronic asthmatic patients requires the close collaboration of several specialists such as allergologists, chest physicians, psychologists, physical therapists, balneologists, etc. Rehabilitation in asthmatic patients may only be considered successful if they resume full-time work (in case they had been in receipt of compensation), if the medical leaves are fewer and shorter and if the drug therapy is reduced or null. The author considers that since bronchial asthma in the whole population of Romania has an incidence of 2.3-2.9% rehabilitation, though costly and sometimes "desperate", is still worth while trying for its medical, economical and psychological implications.

Adolescent↗

Incidence and significance of precipitating antibodies in occupational and non-occupational extrinsic non-atopic (type III) asthma (bronchial asthma with precipitins).

Precipitating antibodies against different organic enviromental dusts were studied in 37 patients with suggestive symptoms of nonatopic bronchial asthma, comparatively with a group of 4 patients with atopic asthma and with a group of asymptomatic subjects, exposed to the same organic dusts as the majority of patients. Precipitins were found present in over 75% of the sera from patients with infectious type non-atopic asthma and were associated with positive semidelayed type skin tests as well as with positive bronchial provocation tests a few hours after antigen inhalation. No precipitins were found in the sera from patients with atopic asthma. Precipitating antibodies were also found but in lower percentages (30%) and at lower titers, in clinically asymptomatic subjects who were occupationally exposed to the respective antigens. It was demonstrated that the presence of precipitins in the sera of patients with bronchial asthma is a valuable diagnostic element which confirms the clinical and anamnestic data. The pathogenic role of precipitins is not yet clear. It might be related to the amount of these precipitins in the serum.

Antigens↗

T and B lymphocytes in respiratory pollen allergies (bronchial pollen asthma and allergic rhinitis).

The T and B lymphocytes were identified by means of the rosette tests in the peripheral blood of 79 patients with respiratory allergies of whom 41 with allergic rhinitis and 38 with bronchial pollen asthma, as well as in 16 control subjects. The results have shown a clear lessening of the T cells (both in per cent and absolute values) and a less significant decrease of the B cells (only in absolute values) in the patients as compared with the controls. These data suggest an immune deficiency which did not differ between the two groups of patients and was not influenced by the specific hyposensitizing treatment.

Adolescent↗