Electron microscopic studies of the isolated fowl embryo otocyst in tissue culture. Rudimentary kinocilia, cup-shaped nerve endings and synaptic bars.
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Animals↗
Biomedical subjects
I Friedmann
Publications and source records attributed to I Friedmann.
Herpes zoster auris associated with facial nerve palsy and auditory nerve symptoms: a case report with histopathological findings.
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Aged↗
Clinico-pathological conference. I. Non-healing nasal granuloma. II.
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Adult↗
Electron-microscope studies of the neuroepithelium of the inner ear in guinea-pigs treated with neomycin.
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Animals↗
Pathology of the ear in the cardioauditory syndrome of Jervell and Lange-Nielsen (recessive deafness with electrocardiographic abnormalities).
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Adolescent↗
Broad-banded striated bodies in the sensory epithelium of the human macula and in neurinoma.
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Adolescent↗
Giant Cell Granuloma Associated with Lesions resembling Polyarteritis Nodosa.
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Journal Article↗
Cystic Pneumatosis of the Large Intestine.
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Cysts↗
Stereocilia-like structures in the endolymphatic sac in Ménière's disease and acoustic neuroma.
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Cilia↗
Rare benign neoplasms of the larynx: rhabdomyoma and lipoma.
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Aged↗
Organ culture of the mammalian and avian embryo otocyst.
The use of a chemically defined medium supplemented with serum has proved most suitable for the growth of the isolated embryonic otocyst in vitro. Complete differentiation of the cochlear duct and of the vestibular apparatus ensued and is described. The system is reliable for organ cultures of both the avian and mammalian otocyst and for the study of various lesions affecting the inner ear and middle ear.
Animals↗
Neuroepithelial changes of the vestibular system in Ménière's disease.
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Humans↗
Tympanosclerosis. An electron microscopic study of matrix vesicles.
The ultrastructure of tympanosclerotic tissue has been studied and compared with other processes of fibrogenesis and calcification. Evidence is presented of the presence of large numbers of extracellular membrane-bound matrix vesicles and their role as the site of primary calcification in tympanosclerosis. Calcified spherular structures are formed and fuse into larger structures lined by a lamina limitans indicating the lines of arrested calcification in the collagenous matrix.
Adult↗
The innervation of the developing fowl embryo otocyst in vivo and in vitro.
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Animals↗
Electron microscopy in head and neck oncology.
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Adenocarcinoma↗
The effect of sodium-cyanide on the chick embryo otocyst in vitro. A tissue culture study.
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Animals↗
Meniére's disease. Electron microscopy of the vestibular ganglion and end organs after ultrasound.
Material for electron microscopy study was obtained from a patient previously suffering from Meniere's disease and treated by ultrasound. It consisted of parts of the membranous labyrinth as well as the vestibular ganglion. The neuro-epithelium of the macula showed degenerative changes and there was marked vacuolation of the cytoplasm. The endothelial cells lining the semicircular canal showed gross vacuoles contained degenerating mitochondria and some debris which may reach the endolymph. The wall of the semi circular canal was oedematous and the basement membrane lifted off by oedematous fluid. There was obvious change in nerves and neurones. The nerves showed loosening of the myelin sheath and ballooning. The neurones contained lipoid inclusions and multicystic lysosomes. Similar inclusions were also noted in some myelinated nerves.
Female↗