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Biomedical subjects

I Franz

Publications and source records attributed to I Franz.

6 recordsLinked to original sources

[Acute appendicitis].

The appendectomy rate in the Federal Republic of Germany has decreased considerably over the past 20 years; in Hannover it has declined by 50%. The number of patients not undergoing operations after hospitalization has increased from 20% to about 65%. Mortality has decreased by 80%, now reaching 0.7 for 100,000 of the population. More than 80% of the deceased are over 65 years old. The main cause of death is advanced appendicitis including perforation. In the North German Patient Appeal Office 10% of all complaints in general surgery concern appendicitis, mostly because of delayed diagnosis. A considerable number of appendectomies is carried out simultaneously in gynecological operations.

Acute Disease

[Comparative in-flight study of a scopolamine-containing membrane plaster versus dimenhydrinate under defined acceleration conditions].

The efficacy and tolerability of Scopoderm TTS (SCOTTS), a transdermal system containing scopolamine, were compared with those of the oral antiemetic dimenhydrinate (double-dummy technique) in a controlled, double-blind, within-patient study including 20 test persons with proven motion sickness. During a 1-h test flight, SCOTTS proved to be as effective as dimenhydrinate. The efficacy and tolerability of both SCOTTS and dimenhydrinate were assessed as to be equally good. Due to its galenic properties, SCOTTS is effective over a 72-h period and therefore is useful in the prevention of motion sickness during long-distance flights, where it is superior to dimenhydrinate.

Acceleration

The presence of a caput epididymidis in congenital absence of the vas deferens.

Experience with 2 patients stimulated a review of the literature on congenital absence of the vas deferens in 133 cases. Bilateral absence was more common and occurred in 80 per cent of the cases, and a caput epididymidis was said to be present in at least 88 per cent. Information concerning the epididymis was lacking in 8.9 per cent of the cases. Two probable explanations for this common clinical finding are offered. Embryologic studies have shown that the caput, unlike the rest of the epididymis, can develop from genital ridge derivatives mainly. This clinical-embryological consideration refutes the common belief that the vas deferens and epididymis as a whole are of mesonephric duct origin. A second, independent factor is the selective blood supply of the caput in some cases. In these cases the caput is preserved by a branch of the testicular artery, perforating the tunica albuginea from within outwards, instead of a branch of the spermatic artery originating from the extratesticular portion of the testicular artery.

Adolescent