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Biomedical subjects

I Franco

Publications and source records attributed to I Franco.

88 records · Page 5Linked to original sources
PubMed1980

[Clinical experience with etomidate].

The effects of Etomidate, a new intravenous anaesthetic agent, were studied in 138 cases which underwent different procedures of variable duration under general anaesthesia. The effects on different organs and systems of this drug, alone or in association with other anaesthetics or adjuvants, were analyzed in this series. Clinical signs, plethysmography and electroencephalography were the main parameters studied. It was shown that Etomidate has a rapid, transient action and a high therapeutic index without any cumulative effects. In conclusion this drug is recommended as an excellent induction agent which could also be advantageously employed for short surgical procedures.

Anesthesia, Intravenous↗
PubMed1977

[Surgical analgesia by acupuncture. Studies of more than 500 cases].

This report was read to the National Congress of the Italian Anaesthesia Society in 1976. A personal series of acupuncture induced anaesthesia is presented and a number of general remarks are made regarding the application of the technique to various areas of surgery.

Acupuncture Therapy↗
PubMedDate not supplied

Comparative safety and efficacy of percutaneous transluminal coronary angioplasty in men and in women.

In early reports of percutaneous transluminal coronary angioplasty (PTCA) in women, the complication rate was higher and the success rate lower than in men. From December, 1980, to December, 1986, 969 women aged 61 (32-84) years and 2,727 men aged 57 (27-84) years underwent PTCA, at our institution. At the time of PTCA 26% of the women had functional class IV angina pectoris compared to 16% of the men (P less than 0.005). Women more often had hypertension (56% vs 39%), left ventricular hypertrophy, diabetes mellitus (19% vs 11%; P less than 0.0005), and family history of coronary artery disease than men. Significantly more of the men (74%) smoked than did the women (53%). The success rate in women was 93% as compared to an angiographic success rate in 2,727 men of 93.5% (ns). The rate of emergency bypass surgery in women was 3.8% as compared to 3.2% in men (ns). The death rate was 0.3% in women as compared to 0.09% in men. Women underwent more PTCA of the left anterior descending coronary artery (52% vs 48% of lesions in men; P less than 0.05) and right coronary artery (32% vs 27% in men; P less than 0.0005). Fewer of the women (9%) had had previous bypass surgery than had the men (15% P less than 0.0005). Procedural details, including balloon diameter, vessel diameter, lesion response pressure, inflation number, and maximum inflation pressures used as PTCA, were not different between men and women. Women had significantly more ST segment shift of 1 mm of more at the time of balloon inflation than men (P less than 0.0005).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMedDate not supplied

Home oxygen delivery system for infants.

Home oxygen programs have evolved to facilitate the discharge of children who have bronchopulmonary dysplasia from neonatal intensive care units. This report describes a method of oxygen delivery for nighttime that is well suited to the home environment. It consists of an "inverted tent" that lines the walls and floor of the crib into which oxygen is flowed via an air entrainment device. This permits rapid equilibration of oxygen up to an FIO2 of 0.40 with a low flow oxygen source from a concentrator. The system is simple, safe, convenient, and economical.

Bronchopulmonary Dysplasia↗
PubMedDate not supplied

Risk factors for recurrent stenosis following successful coronary angioplasty.

The major limitation of coronary angioplasty is recurrent stenosis. Patient, clinical, and procedural factors at the time of angioplasty were correlated with the presence or absence of angiographically documented recurrent stenosis or continued patency. Patients with single-vessel, multilesion disease had a lower incidence of recurrence than those with single-vessel, single-lesion disease (22.2% v 37.3%). Patients with multivessel disease had the highest rate of recurrent stenosis (45%). Sex and age did not predict recurrence. Patients with more severe symptoms, patients without prior myocardial infarction (MI), and insulin-dependent diabetic patients were more likely to have recurrent stenosis. Of the lesion variables, a severe stenosis or a low gradient before angioplasty, the absence of an intimal tear after angioplasty, and left anterior descending artery lesions correlated with a higher recurrence rate. Inflation times greater than or equal to 30 seconds and a greater total number of inflations correlated with a higher recurrence rate. Multivariate analysis showed the following variables to be important predictors of recurrence: Canadian Heart Class, history of myocardial infarction, gradient before angioplasty, artery dilated, number of inflations, severity of stenosis before angioplasty, and insulin-dependent diabetes mellitus.

Adult↗
PubMedDate not supplied

Risk factors for in-hospital mortality associated with coronary angioplasty.

The clinical, angiographic, and procedural findings in 40 in-hospital deaths among 5,000 consecutive percutaneous transluminal coronary angioplasties were reviewed. Compared to the total group, the mortality group had a higher proportion of women, older age, and more extensive coronary disease. Angioplasty was performed as an emergency procedure in 21 of the 40 patients who died. Eighteen presented with an evolving acute myocardial infarction and 17 with unstable angina. Most patients presented in critical condition prior to angioplasty: 18 patients were in cardiogenic shock and 5 patients were on cardiopulmonary resuscitation. Among 13 patients who died following elective angioplasty, the salient feature was acute vessel closure or dissection in 7 patients and failed dilatation of a saphenous vein graft in 4 patients.

Age Factors↗
PubMedDate not supplied

Percutaneous transluminal coronary angioplasty of native coronary arteries via saphenous vein grafts.

We analyzed the immediate and long-term outcome of percutaneous transluminal angioplasty (PTCA) of native coronary arteries via saphenous vein grafts (SVG) in 30 patients. The mean age of the grafts was 69 months. Angioplasty was successful in 27 (90%) patients. One patient died following emergency bypass surgery. There were no distal embolizations and one non-Q myocardial infarction. Follow-up angiography was performed in 12 patients, which revealed restenosis in three patients. At a mean follow-up of 20 months, cumulative survival was 93%. Freedom from myocardial infarction, repeat bypass surgery, and death was 80%. We conclude that PTCA of native coronary arteries via SVG is a safe alternative to repeat CABG in selected patients.

Adult↗