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Biomedical subjects

I Feller

Publications and source records attributed to I Feller.

At least 37 records · Page 2Linked to original sources
PubMed1976

Baseline results of therapy for burned patients.

Baseline results of therapy for burned patients have been determined. The data (21,000 cases) from the National Burn Information Exchange have been analyzed by probit analysis to determine survival as it is influenced by the size and death of the burn, age and sex of patients, topical agents, and the institution providing treatment. The results demonstrate that survival is influenced by the size and depth of the burn; that there is increased survival of males, compared to that of females; that five differnent age categories can be identified that influence survival; that the topical agent used has little effect on survival; and that there is a significant difference in survival when the institution providing the treatment is considered.

Administration, Topical↗
PubMed1976

Effect of cyclophosphamide on the immune response to Pseudomonas aeruginosa in mice.

Natural resistance in mice to Pseudomonas aeruginosa was decreased 10-fold with a single dose of 300 mg of cyclophosphamide (CY) per kg intraperitoneally. Mice were resistant to infection when immunized actively with Pseudomonas vaccine or passively with Pseudomonas immune serum before receiving CY. Syngeneic spleen, thymus and/or bone marrow cells were transfused into CY-treated recipient mice. Protective anti-Pseudomonas antibody was elicited in the recipient mice when they were vaccinated 1 day after receiving normal spleen cells and challenged 8 days after vaccination. When 1.6 X 10(7) normal thymus and bone marrow cells were infused before vaccination, 69% of the recipients of both cell preparations responded serologically compared with 15 and 27% of those receiving either thymus or bone marrow cells, respectively. CY-treated thymus or bone marrow cell recipients were resistant to Pseudomonas infection when 6 X 10(7) of either cell population was transfused.

Animals↗