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Biomedical subjects

I Faris

Publications and source records attributed to I Faris.

At least 19 recordsLinked to original sources
PubMed1995

The fate of the aortofemoral graft.

OBJECTIVE: To determine the incidence and cause for reoperation following aortofemoral bypass surgery. DESIGN: This paper describes the results of all aortofemoral grafts performed in the years 1978-1991, 251 of these patients underwent an aortobifemoral graft (ABF) whilst the remaining 50 had an aortounifemoral graft (AUF). RESULTS: The aortofemoral bypass was the only operation performed in fewer than half of the patients. Sixteen per cent of ABF and 50% of the AUF patients had surgery before the index operation. Subsequently 33% of the ABF patients and 60% of the AUF group had one or more additional vascular procedures. Graft infections and false aneurysms continued to present in about 1% patients per year at least up to 10 years following surgery. The 5 year actuarial survival was 73% in the ABF group and 38% in the AUF patients. The primary patency at 5 years was 85% in the ABF patients and 81% in the AUF group. Amputation was performed in 6% of the ABF patients and in 20% of the AUF patients. CONCLUSIONS: The frequent need for later surgery (1:3 for the ABF patients) should be considered in the decision to undertake the initial aortofemoral operation when the patient presents with intermittent claudication.

Aneurysm, False↗
PubMed1995

Vascular surgery.

Recent developments in vascular surgery have occurred in many areas. The topics of intimal hyperplasia and reperfusion injury are the subject of much current research and possible methods of treatment are at an early stage of development. Advances in perioperative care have contributed to a reduction in mortality and morbidity. Endovascular techniques are being employed widely but the indications for their use are not yet agreed. The laboratory assessment of patients has been enhanced by the availability of duplex ultrasound scanning. The indications for carotid endarterectomy are becoming less controversial and a more aggressive approach is being taken in patients with abdominal aortic aneurysm. In patients with chronic lower limb ischaemia, long bypass grafts to the level of the ankle are being performed more frequently. The use of temporary shunts in patients with major arterial injuries appears to improve the results of treatment.

Humans↗
PubMed1994

Upper extremity arterial injuries: experience at the Royal Adelaide Hospital, 1969 to 1991.

PURPOSE: A review of upper extremity arterial injuries managed at the Royal Adelaide Hospital between 1969 and 1991 was undertaken because the optimal management of complex upper extremity trauma, particularly in proximal injuries, remains unclear. METHODS: Patients were identified from the computer registry of patients treated by the vascular unit at the Royal Adelaide Hospital. They were studied in three groups: (1) subclavian and axillary artery, (2) brachial artery, and (3) radial and ulnar artery injuries. The mechanism of injury, associated injuries, treatment and outcome were reviewed. RESULTS: There were 114 patients with upper extremity arterial injuries: 28 with subclavian and axillary, 62 with brachial, and 24 with radial and ulnar artery injuries. Good upper limb function was obtained in 32% of subclavian and axillary artery injuries, 79% of brachial artery injuries, and all radial and ulnar artery injuries. Amputation was performed in 14% of the proximal injuries and 8% of the brachial artery injuries. Three deaths occurred in this study group. CONCLUSION: Blunt proximal injuries were usually associated with neurologic, soft tissue, and bony damage, which was responsible for the poor functional outcome. Critical limb ischemia or severe hemorrhage rarely occurred. Complete brachial plexus lesions resulted in uniformly poor outcomes. More distal injuries were associated with fewer nerve and soft tissue injuries, resulting in a more satisfactory outcome.

Adolescent↗
PubMed1989

The veno-arteriolar reflex in free skin flaps.

The veno-arteriolar reflex was measured in 10 subjects in whom an area of denervated skin was present in the lower limb following free flap transfer of skin and subcutaneous tissue 3 weeks to 2 years previously. The vasoconstrictor response to dependency was measured in the skin of the flap, in adjacent innervated skin and after chemical dilatation of cutaneous vessels in the skin of the flap. This veno-arteriolar reflex resulting in a reduction of blood flow of 30-40% was present and equal in both normal and denervated skin. The response was abolished by chemical vasodilatation. The results indicate that sympathetic innervation is not essential for the veno-arteriolar reflex, and suggest that myogenic mechanisms may be more important than previously believed.

Adult↗
PubMed1987

Thrombolytic therapy.

Explore the source record for details and available documents.

Arterial Occlusive Diseases↗
PubMed1986

Incidence of the radial steal syndrome in patients with Brescia fistula for hemodialysis: its clinical significance.

The Brescia fistula is the method of choice for providing vascular access in patients who have chronic kidney failure that requires hemodialysis. This study investigated hand hemodynamics in patients with Brescia fistulas to determine the incidence of radial steal and its relationship to symptoms of arterial insufficiency of the hand. Twenty-three patients, one of whom had symptoms of arterial insufficiency, were studied. Thumb systolic blood pressure was determined by photoplethysmography under resting conditions and with the fistula, radial, and ulnar arteries occluded successively by digital pressure. The brachial pressure was determined by Doppler ultrasonography and the thumb/arm pressure ratio was determined for each experimental condition. The presence of a Brescia fistula resulted in a 40% reduction of the thumb blood pressure (median thumb/arm ratio = 0.61), which returned to normal (median ratio = 1.03) when the fistula was occluded. Occlusion of the radial artery distal to the fistula resulted in a significant increase in thumb blood pressure (median ratio = 0.89; p less than 0.001), indicating the presence of radial steal. This phenomenon occurred in 21 of the 24 fistulas (88%) studied. This study demonstrated that the radial steal phenomenon occurs in most patients with Brescia fistulas but in only a small number of these patients do symptoms of arterial insufficiency develop.

Adult↗
PubMed1986

Intra-arterial streptokinase therapy to relieve acute limb ischemia.

One hundred two patients with acute lower limb ischemia were treated with intra-arterial streptokinase. Thirty-seven patients had occluded vascular grafts and sixty-five had had no previous vascular surgery. Eighty-six limbs were acutely threatened. Intra-arterial streptokinase was given as an initial loading dose with a lower maintenance dose given afterward. The mean duration of therapy was 59 hours and hematologic monitoring was meticulous. Indications for intra-arterial streptokinase therapy were contraindication to surgery, anticipation of technically difficult surgery, and multiple occlusions that required separate surgical approaches. Seventy-two legs were saved (71%) and 30 amputated. Morbidity was low and only 1 of the 11 deaths was attributable to streptokinase. No leg was lost that would otherwise have been saved by straightforward surgery and no leg was lost that had not been previously threatened. In 46 patients for whom emergency femorotibial bypass would have been necessary, 35 legs (76%) were saved. Forty-three patients had vascular reconstruction immediately after streptokinase therapy was stopped, to bypass occlusive lesions that had been demonstrated by the thrombolytic therapy in 28 patients, and because streptokinase had produced no response in 15 patients. The advantages of intra-arterial streptokinase in the management of the acutely ischemic leg are that the leg may be saved without surgery, that surgery is not precluded, that the patient can be made as fit as possible for surgery during the streptokinase infusion, and that streptokinase can facilitate surgery by delineating underlying vascular pathologic conditions and clearing distal runoff vessels.

Acute Disease↗
PubMed1985

Skin perfusion pressure in the prediction of healing in diabetic patients with ulcers or gangrene of the foot.

The measurement of skin perfusion blood pressure (SPP) estimated by an isotope clearance technique has been used to predict the healing of ulcers or gangrene of the foot in 61 diabetic subjects. Healing followed conservative treatment or local surgery in 1 of 21 cases if the SPP was less than 40 mm Hg but in 35 of 40 with higher values for SPP. Healing was unlikely if the toe blood pressure was less than 40 mm Hg or the ankle systolic pressure was less than 80 mm Hg. It is recommended that the SPP be measured in patients in whom confident predictions of healing cannot be made on the basis of ankle pressure or other measurements.

Adult↗
PubMed1984

Reconstructive renal vascular surgery for chronic renal failure.

This paper reports the results of reconstructive renal arterial operations on 23 patients who underwent surgery because it was considered that renal artery disease was contributing to their chronic renal failure. The median pre-operative serum creatinine in this group of patients was 0.77 (range 0.15-1.14 mmol/l) and all patients had severe hypertension. In 10 cases there was evidence of other renal disease (analgesic nephropathy, 8; glomerulonephritis, 2). Operation performed was unilateral aortorenal reconstruction in 21 patients and bilateral reconstruction in 2 patients. There were four in-hospital deaths. In 15 patients operation was judged to have improved their renal function with a fall of median pre-operative creatinine from 0.34 mmol/l (0.15-0.84) to a median creatinine of 0.15 (0.05-0.52). There was one intra-operative death. There were 7 patients in whom operation led to no improvement in renal function. Their median pre-operative creatinine was 0.90 (0.32-1.14 mmol/l), and this pre-operative creatinine differs significantly from the group whose creatinine fell after surgery (P less than 0.002). Renal artery reconstruction should be considered in patients with chronic renal failure who have correctable arterial lesions.

Adult↗
PubMed1984

Effect of therapy on 24-h subcutaneous blood flow in the leg in patients with severe ischemia.

The effect of vascular surgical reconstruction or Buerger's exercises upon average subcutaneous blood flow for a 24-h period was studied in 14 patients with severe leg ischemia due to occlusive arterial disease. Blood flow was estimated proximally in the calf and in the foot by a 133Xe washout technique. Seven patients underwent vascular surgery. Postoperatively subcutaneous blood flow increased in the calf and the foot in all patients except one in whom a decrease in blood flow in the foot was seen. In this case a decrease in systolic blood pressure occurred following the operation. Buerger's exercises did not alter subcutaneous blood flow either in the calf or in the foot in the seven patients studied. Buerger's exercises seem to be of no value for these patients. The measurement of blood flow in subcutaneous tissue over a period of 24 h seems to be a useful test of the effect of different treatments.

Aged↗
PubMed1984

Blunt injury to the subclavian artery.

This paper reports two cases of closed injury to the subclavian artery, one resulting from avulsion and the other from compression from a seat-belt. Diagnosis may be delayed because of the absence of both haemorrhage and distal ischaemia. The surgical approach may be via a standard supraclavicular incision, but frequently a combined cervicothoracic approach is necessary.

Accidents, Traffic↗