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Biomedical subjects

I F Grigor'eva

Publications and source records attributed to I F Grigor'eva.

6 recordsLinked to original sources

[Neuropeptides in the treatment of sensorineural hypoacusis in children].

The examination of 250 children with neurosensory hypoacusis (NSH) demonstrated a 78% efficacy of endaural phonophoresis with dalargin (DPP) and transcranial electrostimulation (TCE) for improvement of acoustic function in the presence of positive ultrasound prognosis. Rheoencephalography and biochemical tests show that neuropeptides improve cerebral hemodynamics and normalize metabolism. Both DPP and TCE promote normalization of protein spectrum of the serum. In addition, TCE normalizes serum magnesium levels and its renal elimination, while DPP normalizes serum content of cholesterol.

Adolescent↗

[Results of collalysine treatment of children with adhesive otitis media].

Upon a clinical and audiological examination of 92 children with adhesive otitis media the patients were assigned to standard treatment or to treatment with a new proteolytic enzyme collalysin. The indications to these therapies were based on the degree of cicatrization, hearing loss and the disease duration. Conventional treatment yielded effect only in the disease duration less than 3 years, an insignificant hearing loss and nonsevere tympanic scars. Otoscopic, acoustic and tympanometric improvement after collalysin electrophoresis was observed in marked scars of the tympanic membrane, in a hearing loss by more than 30 dB, in shorter duration of the disease. 80% of the patients on collalysin functionally benefited from the treatment.

Adolescent↗