Rheumatic diseases in aviation medicine.
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Adult↗
Biomedical subjects
I F Anderson
Publications and source records attributed to I F Anderson.
The heart in rheumatoid arthritis: an echocardiographic study.
An echocardiographic study of 44 patients with active rheumatoid arthritis was carried out by means of a Picker ultrasonic laminograph. A posterior pericardial effusion was found in 14 patients (32%) and pericardial thickening in 5 (11%). The maximum amplitude of the anterior cusp of the mitral valve was reduced in 18 patients, and the diastolic (EF) slope was abnormal in 17 patients. The posterior cusp movement and left ventricle diameter were normal. The over-all incidence of cardiac involvement in these patients was 73%. The incidence of heart abnormalities given by echocardiographic diagnosis of cardiac manifestation of rehumatoid arthritis correlates well with the incidence derived from postmortem studies.
Adult↗
Pernicious anaemia with hypogamma-globulinaemia. A case report.
Auto-immune mechanisms are important in the evolution of pernicious anaemia, but cannot be demonstrated in all cases. Cell-mediated immunity is involved in the pathogenesis, and explains the occurrence of pernicious anaemia in patients with hypogammaglobulinaemia. The pernicious anaemia seen in these patients differs in some respects from the classical form of the disease. The case history of a patient with pernicious anaemia and hypogammaglobulinaemia is presented, and the possible pathological mechanisms are discussed.
Adult↗
Gold therapy in rheumatoid arthritis.
Forty patients with active rheumatoid arthritis were treated with intramuscular injections of gold salts. A significant response was shown by 67,5% of the patients. Treatment was discontinued owing to side-effects in 35%. Dermatitis and proteinuria from renal damage were the commonest complications of treatment. The method of treatment and its side-effects are discussed.
Adult↗
Letter: Ulcero-osteolytic neuropathy.
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Bone Resorption↗
Pseudogout--CPPD arthropathy, Case reports.
Pseudogout, or calcium pyrophosphate arthropathy, is a crystalline synovitis, characterised either by acute attacks of joint pain, which usually occur in the large joints, or by a more chronic, progressive form of joint disease. The essential features of the disease are chondrocalcinosis and the presence of pyrophosphate crystals in the synovial fluid. The exact pathogenesis is unknown. Case reports of 2 patients with confiemed pseudogout, and of 1 who is suspected to be suffering from the disease, as well as a summary of the outstanding aspects of the condition, are presented.
Acute Disease↗
Sporadic ulcero-osteolytic neuropathy in Blacks. A report of two cases.
The triad of a peripheral neuropathy, skin ulceration and destruction of bones and joints of the feet is called ulcero-osteolytic neuropathy, when other common causes of similar lesions have been excluded. Malnutrition, alcoholism and local trauma predispose to the development of the condition. It is to be differentiated from burnt-out leprosy, and is a chronic condition that eventually leads to characteristic deformities.
Adult↗
The radiographic appearance of the rheumatoid hand.
The early diagnosis of rheumatoid arthritis ensures a timeous prognosis and appropriate therapy for this chronic disease. The radiograph of the hand is a valuable aid in making this diagnosis, but accurate interpretation is difficult. An outline of the X-ray changes seen in the rheumatoid hand is presented, and the salient points in the differential diagnosis are outlined.
Arthritis↗
Analgesic studies in osteo-arthritis.
Two studies on a total of 45 patients with chronic osteoarthritis using fenoprofen calcium are presented. Different methods using only subjective criteria (pain intensity scores and pain relief scores) are applied. Measurable analgesic qualities were demonstrated for fenoprofen, which is seen as a valuable addition to the drug therapy of osteo-arthritis.
Analgesics↗
Regeneration of the semitendinosus and gracilis tendons following their transection for repair of the anterior cruciate ligament.
Apparent regeneration of the tendons of the semitendinosus and gracilis muscles after their use for anterior cruciate ligament reconstruction was noted during routine follow-up of 225 patients. From this group, four patients were selected for thorough examination, including magnetic resonance imaging, electromyographic studies, strength testing, and clinical examination. The results demonstrate that these tendons appear to regrow and are probably functional.
Anterior Cruciate Ligament↗