Disappearing foot pulses. Report of two cases with isolated stenosis at the bifurcation of the common femoral artery.
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Adult↗
Biomedical subjects
I Eriksson
Publications and source records attributed to I Eriksson.
Retrospective analysis of the efficacy of cefotaxime sodium dosed twice daily. The Swedish experience.
In a Swedish multicenter, comparative, retrospective study, patients with different types of infections--bacteremia-septicemia, genitourinary, intra-abdominal, central nervous system, and lower respiratory tract infections--were randomly selected from the hospital records. Patients treated with cefotaxime twice or three times a day as monotherapy (excluding metronidazole) for at least 1 day (240 cases) were analyzed in terms of clinical and bacteriologic outcome, these results were correlated with the dosing regimen. Similarly high success rates (cure and improvement) at hospital discharge were observed in both group initially treated with cefotaxime 1 g twice daily and 2 g twice daily (97 and 96%, respectively). A total of 73% of patients were initially treated with cefotaxime for only 3 days at most before changing to a lower dose regimen, an alternate intravenous treatment, or oral drug follow-up. Clinical evaluation at hospital discharge revealed a clinical success rate between 87 and 100%, depending on the type of infection.
Adolescent↗
[Reparative surgery of valvular incompetence of the deep veins of the leg].
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Humans↗
Cardiac risk in abdominal aortic surgery.
Seventy-eight patients were included in a prospective study of the cardiac risk in abdominal aortic surgery. The Goldman risk score and the American Society of Anesthesiologists (ASA) classification system were applied besides several individual clinical risk factors. Thirty-three patients developed some kind of cardiac event, 13 of which were myocardial infarctions leading to death in six patients. Computer aided stepwise logistic procedure was used to determine risk factors independently correlated with these complications. This study showed that the Goldman risk score, angina, hypertension and renal insufficiency were significantly correlated with postoperative cardiac complications while no correlations were demonstrated with history of myocardial infarction, chronic heart failure or the ASA score system. A high incidence of cardiac complications (32%) was also found in the low-risk category in the Goldman score system, which indicates the need for cardiac function tests before abdominal aortic surgery.
Aged↗
Surgical treatment of pararenal abdominal aortic aneurysms.
Thirty patients with juxtarenal infrarenal and 16 patients with suprarenal abdominal aortic aneurysms underwent elective (58%) or urgent (42%) repair. Twenty-three patients were hypertensive and 20 had impaired renal function preoperatively. Nineteen patients required combined aortic and renal artery reconstruction, in which reimplantation was the most common technique used. The perioperative mortality rate was 7.4% in the elective group and 36.8% in the urgent group. Rupture of the aneurysm and a preoperative high serum creatinine level were risk factors correlating to early mortality. Among survivors, 61% showed a rise in serum creatinine in the early postoperative period. In all but one the transient renal insufficiency was resolved within one month. Of the hypertensive patients 64% were cured or under control with medication following combined reconstruction. These results demonstrate that surgical repair of pararenal abdominal aortic aneurysms can be performed with an acceptable mortality and morbidity.
Aged↗
Late results after venous valve repair.
Seventeen patients (18 extremities) with primary deep venous insufficiency underwent femoral vein valve repair. Prior to the valvuloplasty the superficial and perforator systems were treated surgically. Dynamic venous pressure measurement and Doppler examination were done for late objective assessment of the valve repair. At early follow-up the reconstructed valves were competent, and all patients showed symptomatical improvement. Significant improvement in pressure reduction and recovery time was observed at postoperative venous pressure measurements. Good or excellent long-term results were obtained in 67% of the extremities after two to five years. Late recurrence of symptoms and incompetence of the reconstructed valve occurred in five extremities. Valve repair may offer good long-term results, but further studies are required to assess the appropriate place of this procedure in the treatment of primary deep venous insufficiency.
Adult↗
Renal complications to left renal vein ligation in abdominal aortic surgery.
Postoperative renal complications have been investigated in 31 patients subjected to left renal vein ligation during abdominal aortic surgery (11 ruptured and 18 non-ruptured aneurysms, 2 occlusive diseases). A marked increase in s-creatinine values was found in all patients after left renal vein ligation. The increase was significantly longer (p less than 0.01) and higher (p less than 0.005) as compared with control patients subjected to abdominal aortic surgery without ligation of the left renal vein. A sustained increase in postoperative s-creatinine values was found in 6 patients, one of whom had a total loss of left kidney function. Left-sided nephrectomy was necessary in 2 patients to control bleeding from the kidney. Acute haemorrhagic infarction and subinfarction of the left kidney were seen in 2 patients. A restricted application of left renal vein ligation during abdominal aortic surgery is recommended.
Aged↗
Mitochondrial sequence variants in patients with schizophrenia.
To investigate whether mitochondrial mutations underly susceptibility to schizophrenia, we sequenced the mtDNAs of two unrelated Swedish patients with schizophrenia and low cytochrome oxidase activity and two maternally related Scottish patients from a family with suspected maternal inheritance of the disease. We found five substitutions in coding regions that have not previously been described as polymorphisms. These new substitutions were studied in 81 schizophrenic patients and five control groups from Sweden and Scotland and found to differ in frequency between populations, emphasizing the importance of using large and well-defined control materials for evaluating the association of mtDNA mutations with disease. The results do not lend strong support to the association of a particular mtDNA substitution with increased risk for schizophrenia. However, the trend towards a higher frequency of substitutions in the patients deserves further attention.
Conserved Sequence↗