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Biomedical subjects

I Eliachar

Publications and source records attributed to I Eliachar.

131 records · Page 8Linked to original sources

Occurrence of additional primary neoplasms in patients with laryngeal carcinoma in Israel (1960-1976).

One thousand-six-hundred and sixty cases of laryngeal cancer were diagnosed in Israel during the years 1960-1976. In 98 of these cases another primary cancer accompanied the laryngeal carcinoma. Patients whose second primary cancer was basal or squamous cell carcinoma of the skin were not included in this study. Therefore, the results reported here deal with 84 patients. The prevalence of multiple primary cancer in patients with laryngeal carcinoma was found to be 5%. Lung cancer is the other primary tumor accompanying laryngeal carcinoma most frequently (29% of the additional tumors) followed by colorectal and bladder cancers. Most of the additional tumors (83%) appeared in a metachronic form with an average time interval of six years. In most metachronic tumors laryngeal carcinoma appeared as the first tumor (86%). Eighty percent of the patients were dead by August 1978. The majority (74%) succumbed due to the additional tumor and only 4% died of laryngeal carcinoma.

Adult↗

Plastipore in reconstruction of the laryngo-tracheal complex.

The feasibility of using plastic material in the reconstruction of the damaged laryngotracheal complex was studied. In 6 dogs, large segments of larynx and trachea were removed and replaced by Plastipore sheets covered on the inside by free skin or mucosa grafts. It was demonstrated that the skin and mucosa covering the Plastipore--and resurfacing the airway's lumen--remained viable. However, there appeared to be inadequate incorporation of the Plastipore into the tissue, probably due to the small pore size. Larger size pores may increase the likelihood that the Plastipore will become firmly embedded in the tissue environment.

Animals↗

Auditory brainstem evoked potentials in insulin-dependent diabetics with and without peripheral neuropathy.

Auditory Brainstem Evoked Potentials (ABEP) were recorded from 33 insulin-dependent diabetes mellitus (IDDM) patients (17 with diabetic peripheral neuropathy and 16 without) as well as from 20 normals. Pure-tone audiometry, speech reception threshold and discrimination were also evaluated. Sub-clinical pure-tone threshold elevation was observed for IDDM patients with neuropathy. Pure-tone thresholds of IDDM patients without neuropathy were not significantly different from those of normals. ABEP abnormality (at 10/sec click rate) was observed in 31% of IDDM patients with neuropathy, rising to 44% when 55/sec click rate measures were included. Abnormalities included bilateral and symmetrical peak-latency prolongations for all waves, greater for the later waves, and prolongation of V-I and V-III interpeak latency differences, all at 10/sec, and only prolonged peak latency for I at increased rate. Abnormalities coincided with microangiopathy and peripheral neuropathy. The incidence of ABEP abnormality for IDDM patients without neuropathy was only 12%, unilateral and sporadic in nature. As a group, IDDM patients with neuropathy had significantly prolonged IV and V peak-latencies, compared with the normals, or with the IDDM patients without peripheral neuropathy. In contrast, IDDM patients without neuropathy resembled the normals in all respects. ABEP have proven useful in understanding the variety of pathologies underlying the clinical manifestation of diabetes.

Adolescent↗

Emergency management of tracheal stenosis. Retrograde tracheal bougienage.

A new technique for immediate though temporary relief of airway obstruction due to tracheal stenosis is described. Introduction of a small gauge cuffed endotracheal tube past the stenotic segment, followed by repeated withdrawal with the cuff inflated, allows for effective and safe retrograde bougienage. Airway patency is maintained throughout. Following this procedure introduction of an endotracheal tube or tracheostomy cannula is facilitated and definitive surgery can be planned.

Emergencies↗