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I Eibschitz

Publications and source records attributed to I Eibschitz.

33 records · Page 2Linked to original sources

Scanning electron microscopy of human Fallopian tube in ectopic pregnancy.

The scanning electron microscopy by virtue of its high resolution topographic reproduction of epithelial surfaces lining the female genital tract, provides unique information toward understanding the anatomy and physiology of the female reproductive system. The human Fallopian ectopic pregnancy is an urgent gynecologic event, which was and still is a diagnostic challenge. There is an increase in the incidence of ectopic pregnancy in recent years. With the purpose of exploring the etiology of tubal ectopic pregnancy from the ultrastructure point of view, we examined 7 cases of tubal pregnancy and compared them to a similar number of normal tubes. We do not find evidence to the pathophysiology of tubal pregnancy by examination of the ultrastructure of the human tube with scanning electron microscopy.

Epithelium↗

Oral contraceptive pills and clinical otosclerosis.

Clinical otosclerosis is a familial disease which is more frequent among women in their reproductive years. The condition usuallly is aggravated by pregnancy. Endocrinologic variables may influence the time of onset and the course of the disease. It is suspected that oral contraceptives (OCs) might stimulate the onset of the disease. Six hundred nulliparous women between the ages of 16 and 30, who used a variety of OCs for 12-36 months, were examined. The hearing of these women was thoroughly investigated. The first audiometric examination of the 600 women revealed three cases (0.5%) of clinical otosclerosis. This incidence is equal to that of the population as a whole, but lower than the incidence found in previously parous women. Audiometric examinations were normal in the remaining 597 women, and repeated examinations revealed no new cases of clinical otosclerosis, despite continuous OC use.

Adolescent↗

Circulation parameters in the human uteroplacental region studied by a radioactive method.

Maternal placental circulation is of great importance, especially in pathological pregnancies, but methods of functional assessment have not been effective. The method used is based on a follow-up of the dynamic behavior of 113mIntracer labeling the mothers's blood at the uteroplacental region. After localization of the placenta two exponential curves of the dynamic behavior of the tracer, one placental and the other myometrial, were obtained. The measurement was made in the third trimester of pregnancy in 30 women with pathological pregnancies and in 51 pregnant control subjects. The clinically sensitive criteria for distinguishing between pathological and control placentas were found to be the ration between the specific blood flow in the placenta and that in the myometrium (lambda p/lambda m) and the slope (alpha) of the straight line passing through the points of this ratio. The value of lambda p/lambda m for pathological pregnancies was 5.4 +/- 1.0 (SD) vs 1.7 +/- 0.6 in control pregnancies, and the value of alpha for pathological cases was 6.3 compared with 1.5 for control subjects. These tests may be useful in the diagnosis of pathological pregnancies with interference in uteroplacental circulation.

Blood Flow Velocity↗

The significance of fetal electrocardiography in the diagnosis of intrauterine bradyarrhythmia.

From 11 cases of fetal bradycardia diagnosed by monitoring of 130 fetal electrocardiograms (ECG's) in high-risk pregnancies we have presented our experience in three selected cases of fetal bradyarrthythmia. Case 1 revealed on ECG blocked atrial premature beats simulating an extreme sinus bradycardia sequentially followed by conducted atrial premature beats. In case 2 we diagnosed ventricular premature beats in the form of persistent bigeminy which was controlled by intravenous propranolol. The last case illustrated the phenomenon of aberrant ventricular conduction known to occur in adult cardiology. The electrophysiologic basis of the variable arrhythmias was discussed. Detailed analysis of repeated direct fetal ECG's provided us with the diagnosis and understanding of the electrophysiologic mechanisms underlying the rhythm disturbances. This consequently determined the pharmacologic therapy and the obstetric approach relevant to each case. We have shown that by direct fetal electrocardiography it is possible to analyze accurately the rhythm disturbances. Persistent fetal bradycardia does not always signify fetal distress. We hope that this will lead to closer teamwork between the obstetrician and the cardiologist which will give an impetus to the future development of "fetal cardiology," thereby enhancing our understanding of the electrophysiology of the fetal heart.

Adult↗

Intrauterine diagnosis and control of fetal ventricular arrhythmia during labor.

A very rare case of a sustained fetal ventricular arrythmia in the form of bigeminy, trigeminy, and quadrigeminy during labor is described. The rhythm distrubance failed to respond to sedatives and narcotics but was successfuly reverted to sinus rhythm following the administration of intravenous propranolol to the mother. The significance and possible mechanism of the arrhythmia is discussed.

Adult↗

Prediction of pregnancy outcome by combined analysis of the fetal electrocardiogram and systolic time intervals.

A microcomputer-based system has been developed that continuously analyzes the fetal electrocardiogram (ECG) and Doppler cardiogram during labor by noninvasive means. Three systolic time intervals (preejection period [PEP], ventricular ejection time [VET], and isovolumetric contraction time), and four ECG parameters (P-R interval, QRS wave duration, T/QRS amplitude ratio, and S-T slope) are simultaneously measured and displayed. Normal values were derived from 126 uncomplicated pregnancies at term. A second group of 89 cases showing fetal heart rate patterns suggestive of fetal distress were subsequently studied: 64 had a good outcome (umbilical artery pH 7.20 or higher and a 5-minute Apgar score 7 or greater) and 25 were asphyxiated. Results were retrospectively analyzed. All asphyxiated fetuses had preejection period, PEP to VET ratio and T to QRS ratio values of more than 1 SD above the mean for the normal population. The PEP to VET ratio, which is an indicator of myocardial function independent of heart rate, proved to be the most sensitive predictor of fetal asphyxia. We conclude that analysis of systolic time intervals and ECG parameters of the fetal heart during labor improves the diagnostic accuracy of fetal heart rate monitoring.

Adult↗

Emergency versus elective microsurgery.

During a 30-months period, a total of 148 microsurgical gynecological operations were performed in our department. We divided these operations into two groups: Emergency microsurgical operations, where microsurgical technique is used in urgent cases for preservation of fertility potential, and elective microsurgical operations, performed for restoration of fertility. We compared the two groups with regard to their inherent characteristics and differences in therapeutic and prognostic approach towards them. The results of our comparison show, that these two groups having in common only the microsurgical approach, are different from each other in the following points: The average age of the emergency microsurgery group was younger since it contained also prefertility cases; the timing of operations in the elective group was always in the proliferative phase of the menstrual cycle; antibiotics were given pre-, intra and postoperatively only in the elective group; corticosteroids were given intra- and postoperatively only in the elective group; the average number of different operative procedures performed during one operation was higher in the restorative group; desire for pregnancy was always present in the restorative and inconstantly in the preservative group; results of the operations regarding intrauterine pregnancy can be evaluated only for the elective, and not for the emergency group. Psychological evaluation of cases can be performed in the elective and not in the emergency group. Because of these differences, a division of microsurgical operations into elective and emergency microsurgery seems justified and valuable to us.

Adolescent↗