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Biomedical subjects

I E Timor-Tritsch

Publications and source records attributed to I E Timor-Tritsch.

12 recordsLinked to original sources

High-frequency transvaginal sonographic examination for the potential malformation assessment of the 9-week to 14-week fetus.

A study was undertaken to evaluate the ability of the high-frequency transvaginal scanning method to consistently image first- and early second-trimester fetal structures, such as body contours, long bones, fingers, face, palate, feet, toes, and the four-chamber view. Ninety-seven low-risk pregnancies were scanned from 9 weeks to 14 menstrual weeks inclusive. Accurate dating was ascertained. The results showed that consistent detection of the respective structures was achieved at the following menstrual ages: sagittal contours at 9 weeks to 10 weeks, long bones at 10 weeks to 11 weeks, fingers at 12 weeks, face and palate at 12 weeks, feet and toes at 13 weeks, and the four-chamber view at 14 weeks. The organs and structures examined could be detected at 9 weeks to 14 weeks inclusive. An increasing number of structure were detected consistently with the increasing menstrual age. The study supports the possibility of searching for specific malformations at or after the menstrual ages mentioned, or performing a more comprehensive malformation evaluation after 13 weeks.

Female

Fetal stomach measurements: not reproducible by the same observer.

We hypothesized that because fetal stomach filling and emptying is a dynamic process, measurements of the stomach dimensions might not be reproducible. Serial measurements 20 minutes apart were made of the stomach in 146 fetuses at 14 to 41 weeks of gestation. In 88 of these fetuses, the biparietal diameter also was measured to provide a standard for comparison. The mean percentage change between each of the paired measurements was 16.6% to 43.1% for the different stomach dimensions, compared with only 2% for the biparietal diameter (P < 0.001). We suggest that caution be excised in the diagnostic use of stomach measurements owing to their dynamically changing nature.

Anthropometry

Transvaginal sonography in gynecologic office practice.

Recent technologic developments have made transvaginal ultrasound an important adjunct to gynecologic examination in both the office and the emergency room settings. Important advantages of using transvaginal ultrasonography to supplement bimanual examination are presented and discussed. Training and equipment issues, as well as medicolegal issues, are addressed.

Equipment Design

Sonographic evolution of cornual pregnancies treated without surgery.

Transvaginal sonography allows early and accurate diagnosis of cornual pregnancy, as well as providing a means for puncture injection treatment of certain ectopic pregnancies. We describe four cases of cornual pregnancy managed nonsurgically and followed with transvaginal sonography for 47-64 weeks. Sonographic evidence of cornual pregnancy persisted throughout the period of follow-up, despite resumption of normal menstrual cyclicity. We conclude that some early live cornual pregnancies can be managed by puncture injection, and cornual pregnancies in which the embryo has died can be followed conservatively.

Female

The discriminatory zone of beta-hCG for vaginal probes.

Recent developments in both laboratory measurements and ultrasound technology have revolutionized the management of early pregnancy. The discriminatory zone concept is a direct result of these developments. By correlating the serum beta-hCG values to the size of an intrauterine gestational sac, a value can be chosen that corresponds to the threshold of visualization of the sac. If the beta-hCG is above this value, a sac must be seen, and if it is not, aggressive steps should be taken to determine whether the pregnancy is abnormal or ectopic. The discriminatory zone may vary among institutions due to different equipment and assays. Thus, its value should be calculated individually at each institution. A proper discriminatory zone and a management protocol such as the one above can eliminate much of the uncertainty in the management of suspected ectopic and early pregnancies.

Chorionic Gonadotropin

Human fetal respiratory movements: a technique for noninvasive monitoring with the use of a tocodynamometer.

A tocodynamometer applied to the maternal abdomen is used for monitoring human fetal respiratory movements (FRM). This provides a recording of fetal chest wall movements from which observations and measurements relating to fetal respiratory physiology may be made. The FRM must be differentiated from materanal vascular and respiratory movements, as well as fetal movements and cardiac pulsations. The technique lends itself to extended periods of observation, since it does not transmit energy to the fetus as in other techniques. The simplicity of the technique, combined with the use of monitoring devices already available in most hospitals, warrants further observation of this method of respiratory movement monitoring in the developing fetus.

Female

Fetal movements associated with fetal heart rate accelerations and decelerations.

In normal pregnant women, the relationship between the FHR and fetal movements (FM) was evaluated during 1,541 consecutive observed FM of at least 1 second's duration. Two observed FHR changes were: (1) accelerations and (2) accelerations followed by decelerations. An acceleration in FHR was observed in association with 91.2 per cent of all FM of 1 to 3 seconds' duration and with 99.8 per cent of FM of longer than 3 seconds' duration. FM were associated with an acceleration followed by a deceleration 66.7 per cent of the time. FM lasting longer than 1 second and associated with neither accelerations nor decelerations were seen 1.8 per cent of the time.

Female