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Biomedical subjects

I E Dovgiĭ

Publications and source records attributed to I E Dovgiĭ.

13 recordsLinked to original sources
PubMedDate not supplied

[Study of the structural changes in irradiated erythrocyte membranes using 2,6-toluidinonaphthalene sulfonate].

It was shown that 2,6-tolyidinonaphthalene sulfonate (2,6-TNS) is localized mainly at the bilayer-water border of the erythrocytic membranes. Under the effect of gamma-radiation the rearrangements occur in the membrane which bring about changes in the distribution of the probe between the membrane and the medium. The lifetime of the excited state of 2,6-TNS after irradiation varies slightly.

Animals↗
PubMedDate not supplied

[Study of the aggregation of membrane proteins of erythrocyte ghosts using SDS-PAAG electrophoresis].

Using the method of electrophoresis in SDS-PAAG the authors showed a diminution of proteins of bands I + II (spectrins) and III (major integral protein) after irradiation of erythrocyte ghosts with doses of 50 to 1000 Gy. We failed to ascertain that radiation-induced lipid peroxidation is involved into membrane protein aggregation. Among the radiolysis products, OH-radicals were shown to contribute markedly to the radiation effect observed.

Animals↗