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Biomedical subjects

I Dotsinsky

Publications and source records attributed to I Dotsinsky.

5 recordsLinked to original sources

Noise sensitivity of three surface ECG fibrillation detection algorithms.

The widening application of automatic external defibrillators (AEDs) presents very strong requirements for external electrocardiogram (ECG) signal analysis. Highly accurate detection of shockable rhythms is required, aimed to approach the maximum of 100% sensitivity and specificity. In a previous study the performance of five well known detection algorithms was assessed by test signals from the ECG-signal databases of the American Heart Association (AHA) and the Massachusetts Institute of Technology (MIT). The results obtained were used as a basis for testing the noise sensitivity of three of these algorithms. Realistic noise was obtained by simulation and recording of signal disturbance by various motions during resuscitation and defibrillation episodes (body shudder convulsions and gasps, cable movement, car transportation). The sensitivity and specificity of the detection algorithms were evaluated using electrocardiogram signals mixed with these noises.

Algorithms↗

Artefact cancellation in motor-sensory evoked potentials: two approaches using adaptive filtration and exponential approximation.

Adaptive filtering for artefact cancellation in motor-sensory evoked potentials using signals obtained by subtraction methods (double-stimulus, off-nerve and subthreshold) is proposed. This is advantageous as inherent non-linear distortions can be overcome in an easier way by adaptive filtering. Efficiency is assessed with reference signals synthesised by varying the shape and reducing the amplitude of a 'pure' evoked potential in the range from 10% to 50%. The experiments show virtually identical shapes of the 'pure' and the filtered signal. The time shift between them is insignificant if a causal filter and small number of Widrow coefficients, e.g. N = 8, are used. Further, two-exponential artefact approximation is applied with subsequent direct subtraction from the contaminated signal by a specially designed PC-controlled system for data acquisition and processing. For a fast procedure convergence, one-parametric optimisation of the time-constant tau is used, starting with tau = 0.5 ms. The results obtained with artefact-corrupted evoked potentials from several subjects prove the efficiency of the approach. It has the substantial advantage of avoiding the need for reference signals. Both methods have advantages compared with other known software techniques.

Electronics, Medical↗

Non-invasive electrogastrography. Part 1: Correlation between the gastric electrical activity in dogs with implanted and cutaneous electrodes.

Experiments were made on dogs with bipolar silver ball-shaped electrodes chronically implanted on the muscle wall of the stomach. The electrical activity of the gastric muscle wall (electrogastromyogram-EGMG) was characterized by slow potential changes during the quiescent period of the migrating myoelectric complex (MMC) and bursts of spike potentials during the activity period of MMC. Cutaneous (surface) electrodes were placed on the abdominal wall. Waves with a rhythm of 4.5-5 cpm were led off by the cutaneous electrodes (electrogastrogram-EGG), simultaneously with the EGMg. The bursts of spike potentials with the slow gastric potentials in the EGMG corresponded to an increase of the amplitude of the waves in the EGG. Good correlation was found between the number and frequency of spike potentials in a group and the wave amplitude in the EGG. EGG recorded on an electrogastrograph designed by us was characterized by low-amplitude waves corresponding to the slow waves during the period of quiescence of MMC and high-amplitude waves corresponding to the bursts of spike potentials during the activity period of MMC. Therefore it is possible to determine the MMC of the stomach by the changes in the amplitude of the waves in the EGG.

Action Potentials↗

Non-invasive electrogastrography. Part 2. Human electrogastrogram.

The electrical activity of human stomach muscle wall-electrogastrogram (EGG), was led off by surface (cutaneous) electrodes placed on the abdominal wall and recorded on an electrogastrograph. A method for complete elimination of the cardiac artefact was elaborated and successfully implemented. It consists of a preliminary elimination of the QRS complex, based on its higher amplitude and slope. The eliminated intervals were replaced by linear segments. A subsequent low-pass filtering allowed to obtain a high quality EGG signal. The electrical activity of the stomach of healthy volunteers was characterized by waves with a frequency of 3.35 +/- 0.09 cpm during the quiescent periods and 2.99 +/- 0.14 cpm during the activity periods of the migrating myoelectrical complex (MMC). Bearing in mind the correlation between the bursts of spike potentials with the slow waves in the dog EGMG and the high-amplitude waves, characterizing the periods of activity in the dog EGG, we can better differentiate the periods of quiescence and activity by the amplitude of the waves. The wave amplitude during periods of quiescence was 81.13 +/- 20.61 microV, significantly different from the wave amplitude during periods of activity being 164.74 +/- 43.34 microV (n = 7). Thus with this method in visual inspection it is possible to identify MMC of the human stomach by the changes in the amplitude of the waves in the EGG.

Action Potentials↗