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Biomedical subjects

I Chanarin

Publications and source records attributed to I Chanarin.

At least 181 records · Page 10Linked to original sources
PubMed1969

Dissociation of intrinsic factor from its antibody: application to study of pernicious anaemia gastric juice specimens.

Intrinsic factor antibody may sometimes be concealed in the gastric secretions of pernicious anaemia subjects, being complexed with residual amounts of intrinsic factor.A method is described for dissociating intrinsic factor from its antibody. Antibody to the vitamin-B(12)-binding site of intrinsic factor was identified in 16 (57%) out of 28 samples of pernicious anaemia gastric juice after dissociation but in only 10 before dissociation. There was no clear relationship between the incidence of antibody in the serum and in the gastric juice of these patients.

Anemia, Pernicious↗
PubMed1968

Absorption and utilization of polyglutamyl forms of folate in man.

Some three-quarters of folate compounds in a normal mixed diet have a chain of seven glutamic acid residues (polyglutamates). The extent to which these forms of folate are absorbed and utilized by man is of considerable nutritional importance. These studies indicate that the polyglutamate forms were absorbed and utilized to about one-third of the extent of simpler (monoglutamate) forms, as judged by the serum folate levels after oral equimolar doses, by the amount incorporated into red cells in long-term studies, by the amount excreted into the urine, and by their capacity to initiate haematological responses in patients with folate-deficient megaloblastic anaemias.

Anemia, Macrocytic↗
PubMed1968

Intrinsic factor.

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Anemia, Pernicious↗